摘要
目的 探究吲哚菁绿荧光腹腔镜下肝细胞肝癌切除手术对患者肝功能及炎症因子的改善情况.方法回顾性分析2022年1-12月宜都市人民医院收治的62例肝细胞肝癌患者的临床资料,根据手术方案不同分为对照组和研究组,各31例.分别实施传统腹腔镜手术、吲哚菁绿荧光腹腔镜手术.比较两组的肝功能、炎症因子水平.结果 治疗前,两组的总蛋白(Total Protein,TP)、白蛋白(Albumin,ALB)、谷丙转氨酶(Alanine Aminotransferase,ALT)、总胆红素(Total Bilirubin,TBIL)比较,差异无统计学意义(P均>0.05);治疗后,研究组的TP、ALB、ALT和TBIL分别为(55.21±3.54)g/L、(36.54±3.24)g/L、(41.02±1.03)g/L、(8.24±1.35)µmol/L,均优于对照组的(50.35±2.97)g/L、(33.35±2.78)g/L、(43.25±1.24)g/L、(10.64±1.05)µmol/L,差异有统计学意义(t=5.856、4.160、7.702、14.975,P均<0.001).研究组的白细胞、降钙素原、C反应蛋白、白细胞介素-6水平均优于对照组,差异有统计学意义(P均<0.05).结论 肝细胞肝癌患者接受吲哚菁绿荧光腹腔镜手术相比于传统腹腔镜手术,在改善肝功能及炎症因子方面效果更好.
Abstract
Objective To investigate the improvement of liver function and inflammatory factors in patients after lapa-roscopic resection of hepatocellular carcinoma with indocyanine green fluorescence.Methods The clinical data of 62 patients with hepatocellular carcinoma admitted to Yidu People's Hospital from January to December 2022 were retro-spective analyzed.According to the surgical plan,they were divided into control group and study group,with 31 cases each.Traditional laparoscopic surgery and green green fluorescent laparoscopic surgery were performed respectively.The liver function and inflammatory factors levels were compared in the two groups.Results Before treatment,there was no statistically significant difference total protein(TP),albumin(ALB),alanine aminotransferase(ALT),and total bilirubin(TBIL)between the two groups(all P>0.05).After treatment,TP,ALB,ALT and TBIL of the study group were(55.21±3.54)g/L,(36.54±3.24)g/L,(41.02±1.03)g/L,(8.24±1.35)µmol/L,respectively,which were better than(50.35±2.97)g/L,(33.35±2.78)g/L,(43.25±1.24)g/L,(10.64±1.05)µmol/L in the control group,the differences were statistically significant(t=5.856,4.160,7.702,14.975,all P<0.001).The levels of leukocytes,procalcitonin,C-reactive protein,and interleukin-6 in the study group were better than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Patients with hepatocellular carcinoma who underwent indocya-nine green fluorescence laparoscopic surgery had better results in improving liver function and inflammatory factors compared with traditional laparoscopic surgery.
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