目的 探究并分析神经内镜治疗颅底肿瘤的应用效果.方法 回顾性选取2019年1月—2021年1月贵阳市第二人民医院收治的50例颅底肿瘤患者的临床资料进行分析,根据治疗方式的差异性进行分组,将采取传统开颅手术治疗的患者(25例)纳入对照组,将采取神经内镜治疗的患者(25例)纳入观察组,对比两组患者的治疗效果.结果 观察组的临床治疗有效率高于对照组,差异有统计学意义(P<0.05).观察组格拉斯哥昏迷量表(Glasgow Coma Scale,GCS)评分为(9.22±0.12)分高于对照组的(8.41±0.11)分,差异有统计学意义(t=24.879,P<0.05).术前,两组炎性因子水平相比,差异无统计学意义(P>0.05).术后,观察组炎性因子水平低于对照组,差异有统计学意义(P<0.05).两组全切除率、复发率相比,差异无统计学意义(P均>0.05).两组不良反应发生率相比,观察组更低,差异有统计学意义(P<0.05).结论 与传统开颅手术相比,神经内镜针对于颅底肿瘤的治疗效果更高,预后改善效果更好,同时能改善体内炎性因子水平,安全性更高.
Effect of the Application of Neuroendoscopy in the Treatment of Skull Base Tumors
Objective To investigate and analyze the application effect of neuroendoscopic treatment of skull base tu-mors.Methods The clinical data of 50 patients with skull base tumors admitted to Guiyang Second People's Hospital from January 2019 to January 2021 were retrospectively selected for analysis.Grouped according to the differences in treatment modalities,patients treated with traditional craniotomy(25 cases)were included in the control group,and pa-tients treated with neuroendoscopy(25 cases)were included in the observation group,and the therapeutic effects of the two groups were compared.Results Compared with the clinical treatment effective rate of the two groups,the ob-servation group was higher,and the difference was statistically significant(P<0.05).The Glasgow Coma Scale(GCS)score of the observation group was(9.22±0.12)points higher than that of the control group(8.41±0.11)points,and the difference was statistically significant(t=24.879,P<0.05).Preoperatively,there was no statistically significant in the levels of inflammatory factors between the two groups compared to each other(P>0.05).Postoperatively,the levels of inflammatory factors were lower in the observation group compared with the two groups,the difference was statistically significant(P<0.05).The total resection rate and recurrence rate were compared between the two groups,the differ-ence was not statistically significant(both P>0.05).The incidence of adverse reactions was lower in the observation group compared with the two groups,the difference was statistically significant(P<0.05).Conclusion Compared with traditional craniotomy,neuroendoscopy has higher therapeutic effect for skull base tumors,better prognosis improve-ment,and also improves the level of inflammatory factors in the body,with higher safety.
NeuroendoscopySkull base tumorTherapeutic effectQuality of life
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