首页|探讨阴道微生态的改变对HPV致宫颈病变的影响

探讨阴道微生态的改变对HPV致宫颈病变的影响

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子宫颈病变的阴道菌种结构复杂性、多样性明显,阴道乳杆菌种类和丰度对阴道微生态平衡起着重要作用,惰性乳杆菌则反之;犬布鲁氏菌、戴阿李斯特琥珀酸纤毛杆菌、阴道加德纳菌和短普雷沃菌与人类乳头瘤病毒(Human Papillomavirus,HPV)感染致宫颈病变密切相关.维持阴道微生态平衡可有效地消除病毒,防止宫颈癌的发生.本研究就阴道微生态的改变对HPV致宫颈病变的影响进行探讨.
Exploring the Effect of Altered Vaginal Microecology on HPV-caused Cer-vical Lesions
The complexity and diversity of vaginal bacterial structures in cervical lesions are obvious,and the species and abundance of Lactobacillus vaginalis play an important role in the vaginal microecological balance,while inert Lactobacillus inertia is vice versa.Brucella canis,Ciliobacterium dyeriensis succinate,Gardnerella vaginalis and Pre-votella short are closely associated with human papillomavirus(HPV)infection causing cervical lesions.Maintaining vaginal microecological balance can effectively eliminate the virus and prevent cervical cancer.In this study,we inves-tigated the effect of vaginal microecological changes on HPV-caused cervical lesions.

High-throughput sequencingHuman papillomavirusVaginal microecologyCervical lesions

田丽君、石继海、余艳琴、于涵、贾喜梅

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包头医学院第一附属医院妇产科,内蒙古包头 014010

包头医学院第一附属医院流行病学研究中心,内蒙古包头 014010

高通量测序 人乳头瘤病毒 阴道微生态 宫颈病变

自治区卫生健康科技计划(2022)包头市卫生健康科技计划

202202243wsjkkj002

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(1)
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