Analysis of the Application Value of Coagulation Function,Platelet Count,and Liver Function Indexes to Different Types of Liver Cirrhosis
Objective To analyze the coagulation parameters and platelet count indexes of different types of cirrhosis(hepatitis B,alcoholic and autoimmune),and to explore the significance of the differences in coagulation indexes of cir-rhosis caused by different etiologies.Methods The clinical data of 90 patients with cirrhosis admitted to the clinical Department of Zhenjiang Third People's Hospital from January 2021 to January 2023 were retrospectively analyzed.According to the disease cause,the patients with cirrhosis were divided into hepatitis B group,alcoholic cirrhosis group and autoimmune cirrhosis group,with 30 cases in each group.The coagulation parameters,liver function in-dexes and platelet indexes of the 3 groups were compared.Results The levels of prothrombin time(PT),international standardized ratio(INR),activated partial thromboplastin time(APTT),and thrombin time(TT)in patients with hepati-tis B group and alcoholic cirrhosis group were higher than those with autoimmune cirrhosis group,and the differences were statistically significant(all P<0.05).The levels of fibrinogen(FIB)in patients with hepatitis B group and alco-holic cirrhosis group were lower than those with autoimmune cirrhosis group,and the difference was statistically sig-nificant(P<0.05).The levels of alanine aminotransferase(ALT)and aspartate aminotransferase(AST)in alcoholic cir-rhosis group and hepatitis B cirrhosis group were lower than those in autoimmune cirrhosis group,and the differences were statistically significant(all P<0.05).The levels of platelet count(PLT)and plateletcrit(PCT)in the hepatitis B cirrhosis group and alcoholic cirrhosis group were lower than those in the autoimmune cirrhosis group,and the differ-ences were statistically significant(all P<0.05).Conclusion In terms of coagulation function,platelet count and liver function indexes,different types of cirrhosis(hepatitis B,alcoholic,autoimmune)patients have differences,which can be used by clinics to diagnose the type of cirrhosis.
Hepatitis B cirrhosisAlcoholic cirrhosisAutoimmune cirrhosisCoagulation parameters
万方数据
维普
