Clinical Analysis of Medroxyprogesterone Acetate Tablets in the Treat-ment of Abnormal Uterine Bleeding in Perimenopause
Objective To explore the effectiveness of medroxyprogesterone acetate tablets in the treatment of abnormal uterine bleeding during perimenopause.Methods A total of 80 patients with abnormal perimenopausal uterine bleed-ing from the People's Hospital of Zhongshan Torch Development Zone from October 2021 to October 2023 were se-lected as the study objects and grouped by dice method,with 40 cases in each control group and reference group.The former was treated with medroxyprogesterone acetate tablets and the latter with mifepristone.Compare the effects of the two groups.Results After treatment,compared with the reference group,the time to control bleeding and complete hemostasis in the control group was shorter,and the differences were statistically significant(both P<0.05).The endo-metrial thickness of the control group was lower than that of the reference group,and the erythrocyte volume and hemo-globin were higher than that of the reference group,and the differences were statistically significant(all P<0.05).Es-tradiol,FSH,luteinizing hormone and progesterone in control group were lower than those in reference group,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the control group was 5.00%,which was lower than that in the reference group(25.00%),and the differences were statistically significant(χ2=6.274,P<0.05).Conclusion Abnormal perimenopausal uterine bleedirg is well treated with medroxyprogesterone acetate tablet,and improves the therapeutic effect.
Medroxyprogesterone acetate tabletsPerimenopauseAbnormal uterine bleedingIncidence of adverse reactions