首页|Ca125、CEA、TSGF和SCC检验在宫颈癌诊断中的价值研究

Ca125、CEA、TSGF和SCC检验在宫颈癌诊断中的价值研究

扫码查看
目的 分析血清糖类抗原(Carbohydrate Antigen 125,Ca125)、癌胚抗原(Carcinoembryonic Antigen,CEA)、特异生长因子(Tumor Specific Growth Factor,TSGF)和鳞状细胞癌抗原(Squamous Cell Carcinoma Antigen,SCC)检验在宫颈癌诊断中的价值.方法 回顾性分析2022年3月—2023年2月牟平区中医医院收治的68例宫颈癌患者资料,将其作为研究组;回顾性分析同期收治的66例宫颈良性疾病患者资料,将其作为对照组.两组患者均接受Ca125、CEA、TSGF和SCC检验.比较Ca125、CEA、TSGF、SCC联合检验与单独检验对于宫颈癌的诊断效能.结果 研究组Ca125(49.65±10.23)U/mL、CEA(13.98±4.02)μg/L、TSGF(86.65±12.02)U/mL、SCC(11.89±2.56)μg/L的检验水平均高于对照组(15.65±11.02)U/mL、(3.28±0.98)μg/L、(52.02±10.23)U/mL、(2.02±1.89)μg/L,差异有统计学意义(t=18.517、21.024、17.935、20.783,P均<0.05).联合检验对宫颈癌的诊断灵敏度、特异度、准确度高于单独Ca125、CEA、TSGF、SCC检验,差异有统计学意义(P均<0.05).结论 宫颈癌患者血清Ca125、CEA、TSGF、SCC表达水平明显升高,且联合检验进一步提高了诊断效能.
Value of Ca125,CEA,TSGF and SCC Tests in the Diagnosis of Cervical Cancer
Objective To analyze the value of carbohydrate antigen 125(Ca125),carcinoembryonic antigen(CEA),tu-mor specific growth factor(TSGF)and squamous cell carcinoma antigen(SCC)in the diagnosis of cervical cancer.Methods The data of sixty-eight patients with cervical cancer treated in Muping District Hospital of Traditional Chi-nese Medicine from March 2022 to February 2023 were retrospectively analyzed as the study group.The data of sixty-six patients with benign cervical diseases treated in the same period were retrospectively analyzed and used as the con-trol group.Both groups underwent Ca125,CEA,TSGF and SCC tests.The diagnostic efficacy of Ca125,CEA,TSGF,SCC combined test and single test for cervical cancer were compared.Results The levels of Ca125(49.65±10.23)U/mL,CEA(13.98±4.02)μg/L,TSGF(86.65±12.02)U/mL and SCC(11.89±2.56)μg/L in the study group were higher than those in the control group(15.65±11.02)U/mL,(3.28±0.98)μg/L,(52.02±10.23)U/mL,(2.02±1.89)μg/L,the differences were statistically significant(t=18.517,21.024,17.935,20.783,all P<0.05).The sensitivity,specificity and accuracy of combined test for cervical cancer were higher than those of Ca125,CEA,TSGF and SCC alone,the differences were statistically significant(all P<0.05).Conclusion The expression levels of serum Ca125,CEA,TSGF and SCC in patients with cervical cancer were significantly increased,and the combined test further improved the diag-nostic efficiency.

Carbohydrate antigen 125Carcinoembryonic antigenTumor specific growth factorSquamous cell carcinoma antigenCervical cancer

丛日娟、姜贝贝、陈玫君

展开 >

山东省烟台市牟平区中医医院检验科,山东烟台 264100

血清糖类抗原 癌胚抗原 特异生长因子 鳞状细胞癌抗原 宫颈癌

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(3)
  • 15