Analysis of Influencing Factors of Progressive Intracranial Hemorrhage af-ter Traumatic Brain Injury
Objective To analyze the clinical value of the combination of thrombelastogram and coagulation function test in predicting progressive hemorrhagic injury(PHI)after trauma.Methods The clinical data of 141 patients with traumatic intracranial hemorrhage treated in the Department of Neurosurgery of Wuzhou People's Hospital from Janu-ary 2016 to August 2022 were retrospectively selected,and the patients were divided into group A and group B accord-ing to whether there was progressive intracranial hemorrhage.Group A(71 cases)included patients with progressive intracranial hemorrhage,and group B(70 cases)included patients without progressive intracranial hemorrhage.At ad-mission,the coagulation function,thromboelastography and head CT examination were performed in both groups,and various indicators of the patients were recorded.Head CT was reviewed 72 h after admission to compare the changes of intracranial hemorrhage between the two groups,and the results were compared 3 months after discharge.Results Logistic regression analysis showed that D-dimer(D-D),thrombin time(TT),reaction time(R)and platelet aggrega-tion function(MA value)were the influencing factors for rebleeding in early intracerebral hemorrhage patients,among which D-D,TT,R time and MA value were the risk factors for the occurrence of PHI(OR=2.744,1.716,12.992,1.635,all P<0.05).ROC curve evaluated the predictive efficacy of the above related indicators,and the AUC of D-D,TT,R time and MA value in predicting patients with progressive intracranial hemorrhage was 0.946,0.800,0.978 and 0.964,respectively(all P<0.05).Conclusion D-D,TT,R time and MA value were the influencing factors of PHI occurrence in patients of traumatic brain injury.Therefore,thrombologram and coagulation function measurement can effectively predict the probability of progressive intracranial hemorrhage,and patients with prolonged D-D,TT,R time and low MA value should be vigilant about the occurrence of intracranial rehemorrhage.
NETL
NSTL
万方数据
维普
