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布地奈德联合鼻内镜手术治疗鼻窦炎-鼻息肉的疗效研究

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目的 研究布地奈德联合鼻内镜手术治疗鼻窦炎-鼻息肉的临床疗效.方法 选取2020年3月—2023年4月南京市溧水区人民医院(东南大学附属中大医院溧水分院)收治的187例鼻窦炎-鼻息肉患者作为研究对象,采用随机数表法将患者分为研究组(n=94)和对照组(n=93).研究组实施鼻内镜手术联合布地奈德治疗,对照组采用鼻内镜手术治疗.对比两组患者炎性因子水平、临床疗效、术后不良反应及复发率.结果 治疗后,研究组各项炎性因子水平低于对照组,差异有统计学意义(P均<0.05);研究组治疗有效率(98.94%)高于对照组(91.40%),差异有统计学意义(χ2=5.799,P=0.016).研究组术后不良反应发生率为4.25%,与对照组的5.38%对比,差异无统计学意义(χ2=0.128,P=0.720).研究组复发率为6.38%,与对照组的7.53%对比,差异无统计学意义(P>0.05).结论 布地奈德联合鼻内镜手术治疗鼻窦炎-鼻息肉疗效显著,能够降低患者体内炎性因子水平,提高治疗有效率,并且安全性较高.
Study on the Efficacy of Budesonide Combined with Nasal Endoscopic Sur-gery in the Treatment of Sinusitis-nasal Polyps
Objective To study the clinical efficacy of budesonide combined with nasal endoscopic surgery for the treatment of sinusitis-nasal polyps.Methods 187 patients with sinusitis-nasal polyps admitted to Lishui District People's Hospital(Lishui Branch of Zhongda Hospital Affiliated to Southeast University)from March 2020 to April 2023 were selected as the study objects,and they were divided into the study group(n=94)and control group(n=93)by using the method of randomized numerical table.The study group was treated with nasal endoscopic surgery com-bined with budesonide,and the control group was treated with nasal endoscopic surgery.Inflammatory factor levels,clinical efficacy,postoperative adverse reactions and recurrence rate were compared between the two groups.Results After treatment,the levels of various inflammatory factors in the study group were lower than those in the control group,the differences were statistically significant(all P<0.05).The treatment efficiency of the study group(98.94%)was higher than that of the control group(91.40%),the difference was statistically significant(χ2=5.799,P=0.016).The incidence rate of postoperative adverse reactions in the study group was 4.25%,compared to 5.38%in the control group,the difference was not statistically significant(χ2=0.128,P=0.720).The recurrence rate in the study group was 6.38%,compared to 7.53%in the control group,the difference was not statistically significant(P>0.05).Conclusion Budesonide combined with nasal endoscopic surgery for the treatment of sinusitis-nasal polyp efficacy is remarkable,can reduce the patient's body inflammatory factors and improve the effectiveness of treatment with higher safety.

BudesonideNasal endoscopySinusitisNasal polypInflammatory factorClinical efficacy

赵上龙、宋省官、胡长安

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南京市溧水区人民医院(东南大学附属中大医院溧水分院)耳鼻咽喉科,江苏南京 211200

布地奈德 鼻内镜 鼻窦炎 鼻息肉 炎性因子 临床疗效

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(4)
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