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兰索拉唑与奥美拉唑治疗十二指肠溃疡的效果对比

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目的 研究兰索拉唑与奥美拉唑治疗十二指肠溃疡的效果.方法 选取2022年7月—2023年7月德兴市人民医院收治的75例十二指肠溃疡患者为研究对象,用随机数表法分为观察组(n=38,兰索拉唑治疗)与对照组(n=37,奥美拉唑治疗),比较两组患者症状改善用时、白介素-6(Interleukin-6,IL-6)以及C反应蛋白(C-reactive Protein,CRP)指标数值、生活质量评分.结果 治疗前,两组患者炎性因子指标、生活质量评分比较,差异无统计学意义(P均>0.05);治疗后,观察组的CRP、IL-6、症状维度评分低于对照组,改善用时少于对照组,功能维度评分、总健康评分高于对照组,差异有统计学意义(P均<0.05).结论 临床上给予十二指肠溃疡患者兰索拉唑治疗,可以减轻机体炎症反应,缩短症状改善用时,提升患者生活质量.
Comparison of Efficacy of Lansoprazole and Omeprazole in the Treatment of Duodenal Ulcer
Objective To study the effect of lansoprazole and omeprazole on duodenal ulcer.Methods A total of 75 patients with duodenal ulcer admitted to Dexing People's Hospital from July 2022 to July 2023 were selected as the study subjects and divided into observation group(n=38,Lansoprazole treatment)and control group(n=37,omeprazole treatment)by random number table method.Symptom improvement time,interleukin-6(IL-6)and C-reactive protein(CRP)indexes,and quality of life score were compared between the two groups.Results Before treatment,there was no statistically significant difference in inflammatory factors and quality of life scores between the two groups(all P>0.05).After treatment,CRP,IL-6 and symptom dimension scores in the observation group were lower than those in the control group,the improvement time was less than that in the control group,and functional dimension score and to-tal health score were higher than those in the control group,the differences were statistically significant(all P<0.05).Conclusion Clinical treatment of lansoprazole in patients with duodenal ulcer can reduce inflammation,shorten symp-toms and improve patients'quality of life.

Duodenal ulcerLansoprazoleOmeprazoleSymptoms improvedQuality of life

郭亚琴、邱和生

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德兴市人民医院消化内科病房,江西上饶 334200

德兴市人民医院内四科,江西上饶 334200

十二指肠溃疡 兰索拉唑 奥美拉唑 症状改善 生活质量

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(4)
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