首页|分析血管内介入治疗与显微镜下开颅手术夹闭颅内动脉瘤的治疗效果差异

分析血管内介入治疗与显微镜下开颅手术夹闭颅内动脉瘤的治疗效果差异

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目的 比较血管内介入治疗与显微镜下开颅手术夹闭针对颅内动脉瘤患者的治疗效果差异.方法 回顾性选取2020年6月—2023年5月济南市济阳区人民医院收治的97例颅内动脉瘤患者的临床资料,根据治疗方式的不同分为两组,对照组(n=48)采用显微镜下开颅手术夹闭治疗,观察组(n=49)实施血管内介入治疗,比较两组患者的临床疗效.结果 观察组治疗总有效率(95.92%)高于对照组(79.17%),差异有统计学意义(χ2=6.276,P=0.012).观察组术后3个月的血管假性血友病因子、内皮素-1水平低于对照组,一氧化氮水平均高于对照组,差异有统计学意义(P均<0.05).观察组术中出血量少于对照组,观察组手术时间、住院时间均短于对照组,差异有统计学意义(P均<0.05).结论 在开展对颅内动脉瘤的治疗中,血管内介入治疗比显微镜下开颅手术夹闭效果更显著,可明显改善患者的血管内皮功能.
Analyzing the Difference in Therapeutic Effects between Endovascular In-tervention and Microscopic Craniotomy Clamping of Intracranial Aneu-rysms
Objective To compare the difference in treatment effect between endovascular intervention and micro-scopic craniotomy clamping for patients with intracranial aneurysms.Methods The clinical data of 97 patients with in-tracranial aneurysms admitted to Jiyang District People's Hospital in Jinan City from June 2020 to May 2023 were ret-rospectively selected and divided into two groups based on different treatment methods.The control group(n=48)re-ceived microscopic craniotomy clamping treatment,while the observation group(n=49)received endovascular interven-tion treatment.The clinical efficacy of the two groups of patients was compared.Results The total effective rate of treatment in the observation group(95.92%)was higher than that in the control group(79.17%),and the difference was statistically significant(χ2=6.276,P=0.012).The levels of von Willebrand factor and endothelin-1 were lower and nitric oxide was significantly higher in the observation group compared to the control group at 3 months postopera-tively,and the differences were statistically significant(all P<0.05).The intraoperative bleeding of the observation group was less than that of the control group,and the operation time and hospitalization time of the observation group were shorter than those of the control group,and the differences were statistically significant(both P<0.05).Conclu-sion In carrying out the treatment of intracranial aneurysm,the effect of endovascular interventional therapy is more significant than microscopic craniotomy clamping,and the patient's vascular endothelial function is significantly im-proved.

Intracranial aneurysmEndovascular interventional therapyMicroscopic craniotomyTherapeutic effect

高磊、郑玉梅

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济南市济阳区人民医院神经外科,山东济南 251400

济南市济阳区人民医院门诊护理部,山东济南 251400

颅内动脉瘤 血管内介入治疗 显微镜下开颅手术夹闭 治疗效果

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(4)
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