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地屈孕酮用于先兆流产保胎治疗中的临床安全性

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目的 分析先兆流产保胎中地屈孕酮的安全性.方法 选取山东省成武县人民医院于2022年10月—2023年10月收治的98例先兆流产保胎患者作为研究对象,用掷骰子的方式分为参考组(行黄体酮治疗)和调查组(行地屈孕酮治疗),各49例.比较两组患者激素指标,恢复时间、治疗有效率、不良反应发生率.结果 治疗前,两组患者激素指标比较,差异无统计学意义(P>0.05);治疗后,调查组激素指标、治疗总有效率均高于参考组,恢复时间短于参考组,不良反应总发生率低于参考组,差异有统计学意义(P均<0.05).结论 地屈孕酮安全性高,能调节孕激素水平,提升保胎有效率.
Clinical Safety of Dydrogesterone in the Treatment of Fetal Preservation in Threatened Abortion
Objective To analyze the safety of dydrogesterone in fetal preservation in threatened abortion.Methods A total of 98 patients with threatened abortion who were treated in Chengwu County People's Hospital of Shandong Prov-ince from October 2022 to October 2023 were selected as the study objects.They were divided into reference group(treated with progesterone)and investigation group(treated with dydrogesterone)by means of dice rolling,with 49 cases in each group.Hormone indexes,recovery time,effective rate of treatment and incidence of adverse reactions were compared between the two groups of patients.Results Before treatment,there was no significant difference in hormone indexes between the two groups(P>0.05);after treatment,the hormone index and total effective rate of the in-vestigation group were higher than that of the reference group,the recovery time was shorter than that of the reference group,and the total incidence of adverse reactions was lower than that of the reference group,and the differences were statistically significant(all P<0.05).Conclusion Dydrogesterone has high safety,can regulate the level of progester-one,improve the efficiency of fetal protection.

DydrogesteroneSecurityThreatened abortionClinical effectPrevent miscarriage

单士超、宋敏、张岩

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山东省成武县人民医院产科,山东菏泽 274200

地屈孕酮 安全性 先兆流产 临床疗效 保胎

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(4)
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