Clinical Effect of Atorvastatin Calcium in the Treatment of Cognitive Dys-function after Cerebral Infarction
Objective To explore the value of atorvastatin calcium in the adjuvant treatment of cognitive dysfunction after cerebral infarction.Methods A total of 80 patients with cognitive dysfunction after cerebral infarction from the pharmacy department of Yixing Sixth People's Hospital Jiangsu Province from January 2021 to June 2023 were se-lected as the study objects.Random number table method was used to divide them into the control group(n=40,clopi-dogrel treatment)and the study group(n=40,atorvastatin calcium assisted treatment on the basis of control group).The total clinical effective rate,incidence of adverse reactions,neurological impairment,cognitive function,quality of daily life,ability of daily living scores and blood lipid level were compared between the two groups of patients.Results The total effective rate of the study group(95.00%)was higher than that of the control group(80.00%),and the difference was statistically significant(χ2=4.114,P<0.05).There were no statistically significant differences in the scores of neu-rological impairment,cognitive function,quality of daily life and ability of daily living between two groups before treat-ment(all P>0.05).The score of neurological impairment in the study group after treatment was lower than that in con-trol group,the score of cognitive function,quality of daily life and ability of daily living after treatment was higher than those in control group,and blood lipid levels(cholesterol,triglyceride,low density lipoprotein and high density lipopro-tein)in the study group were better than those in the control group after treatment,and the difference was statistically significant(all P<0.05).There was no statistically significant difference in the incidence of adverse reactions between groups(P>0.05).Conclusion Atorvastatin calcium assisted in the treatment of cognitive dysfunction after cerebral in-farction can acheive a significant effect.
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NSTL
万方数据
维普
