首页|妥布霉素地塞米松滴眼液对白内障术后干眼症患者眼部症状改善情况和泪膜稳定性的影响

妥布霉素地塞米松滴眼液对白内障术后干眼症患者眼部症状改善情况和泪膜稳定性的影响

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目的 探究妥布霉素地塞米松滴眼液对白内障术后干眼症患者眼部症状改善情况和泪膜稳定性的影响.方法 选取2022年7月—2023年6月南京市六合区中医院收治的98例白内障手术后发生干眼症的患者为研究对象,经电脑随机分为两组,对照组(49例)行重组牛碱性成纤维细胞生长因子眼用凝胶治疗,观察组(49例)配合运用妥布霉素地塞米松滴眼液治疗.经过30 d的持续治疗,对比两组眼部症状、泪膜稳定性、不良反应发生情况.结果 观察组眼表疾病指数量表(Ocular Surface Disease Index,OSFI)评分和角膜荧光染色(Corneal Fiuoresence Staining Score,CFS)评分低于对照组,差异有统计学意义(P均<0.05);治疗后,观察组泪膜破裂时间、泪液分泌试验、泪膜厚度指标均优于对照组,差异有统计学意义(P均<0.05);观察组不良反应发生率为8.16%,低于对照组的12.24%,差异无统计学意义(χ2=0.446,P=0.505).结论 妥布霉素地塞米松滴眼液能够良好治疗白内障术后干眼症患者,改善眼部症状,保持泪膜稳定.
Effects of Tobramycin Dexamethasone Eye Drops on the Improvement of Ocular Symptoms and Tear Film Stability in Patients with Dry Eye after Cataract Surgery
Objective To investigate the effects of tobramycin dexamethasone eye drops on the improvement of ocular symptoms and tear film stability in patients with dry eye after cataract surgery.Methods A total of 98 patients with dry eye after cataract surgery treated in Nanjing Lihe District Hospital of Traditional Chinese Medicine from July 2022 to June 2023 were selected as the study subjects.They were randomly divided into two groups by computer.The con-trol group(49 cases)received recombinant bovine basic fibroblast growth factor eye gel treatment,and the observation group(49 cases)received tobramycin and dexamethasone eye drops treatment.After 30 days of continuous treatment,the ocular symptoms,tear film stability and adverse reactions occurence of the two groups were compared.Results The ocular surface disease index(OSFI)scores and corneal fiuoresence staining(CFS)scores in the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).After treat-ment,the indexes of tear film breakup time,Schirmer Ⅱtext and tear film thickness in observation group were better than those in control group,and the differences were statistically significant(all P<0.05).The incidence of adverse re-actions in the observation group was 8.16%,lower than 12.24%in the control group,and the difference was not statis-tically significant(χ2=0.446,P=0.505).Conclusion Tobramycin dexamethasone eye drops can be a good treatment for patients with dry eye after cataract surgery,promoting benign improvement of ocular symptoms and maintaining tear film stability.

Tobramycin dexamethasone eye dropsCataract surgeryDry eyeOcular symptomsTear film stabilization

蒋宁

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南京市六合区中医院眼科,江苏南京 211500

妥布霉素地塞米松滴眼液 白内障手术 干眼症 眼部症状 泪膜稳定性

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(5)
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