Study on the Clinical Effectiveness of Piperacillin Sodium Tazobactam in the Treatment of Severe Sepsis
Objective To study the clinical effect of piperacillin sodium tazobactam in the treatment of severe sepsis.Methods A total of 62 patients with severe sepsis admitted to the Department of Critical Care Medicine of Huangdao District Hospital of Traditional Chinese Medicine from January 2021 to October 2023 were selected as the study ob-jects,and were divided into two groups according to randomized numerical table method,with 31 cases in each group.Cefotaxime sodium was used in the comparison group and piperacillin sodium tazobactam was used in the study group.The symptom scores,inflammatory factor levels,immunoglobulin levels,therapeutic effectiveness,and adverse effects were compared between the two groups.Results After treatment,the symptom score,level of inflammatory factors of the study group were lower than those of the comparison group,the immunoglobulin level of the study group was higher than that of the comparison group,and the differences were statistically significant(all P<0.05).The therapeu-tic effectiveness of the study group was higher than that of the comparison group,the incidence rate of adverse reac-tions in the study group was lower than that in the comparison group,and the differences were statistically significant(both P<0.05).Conclusion Piperacillin sodium tazobactam is selected for the treatment of patients with severe sepsis has a high effect,can alleviate the symptoms such as panic in patients,reduce the inflammatory response of the body,and the adverse reaction situation is less.
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