首页|盐酸美金刚联合重酒石酸卡巴拉汀治疗中度阿尔茨海默病患者的临床效果研究

盐酸美金刚联合重酒石酸卡巴拉汀治疗中度阿尔茨海默病患者的临床效果研究

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目的 探讨在中度阿尔茨海默病患者治疗中采用盐酸美金刚联合重酒石酸卡巴拉汀治疗的价值.方法 选取2021年10月—2023年9月大连市金州区第四人民医院收治的79例中度阿尔茨海默病患者为研究对象,采取信封法分为研究组(39例)和比较组(40例),比较组应用重酒石酸卡巴拉汀治疗,研究组在比较组治疗基础上加用盐酸美金治疗.比较两组治疗效果、临床指标及炎性因子.结果 研究组的治疗总有效率为100.00%,高于比较组的85.00%,差异有统计学意义(χ2=4.374,P=0.036).治疗后,研究组临床指标优于比较组,差异有统计学意义(P<0.05).治疗后研究组炎性因子水平优于比较组,差异有统计学意义(P<0.05).结论 在中度阿尔茨海默病患者治疗中采取盐酸美金刚联合重酒石酸卡巴拉汀治疗方案,可以提高临床疗效,优化临床指标,缓解炎症反应.
Clinical Effect of Memantine Hydrochloride Combined with Cabalatin Bi-tartrate in the Treatment of Patients with Moderate Alzheimer's Disease
Objective To investigate the value of memantine hydrochloride combined with cabalatine bitartrate in the treatment of moderate Alzheimer's disease.Methods A total of 79 patients with moderate Alzheimer's disease admit-ted to the Dalian Jinzhou District Fourth People's Hospital from October 2021 to September 2023 were selected as the study objects.They were divided into a study group(39 cases)and a comparison group(40 cases)by envelope method.The comparison group was treated with cabalatine bitartrate,while the study group was treated with memantine hydro-chloride based on the comparison group's treatment.The therapeutic effect,clinical indexes and inflammatory factors of the two groups were compared.Results The total effective rate of treatment in the study group was 100.00%,which was higher than 85.00%in the comparison group,and the difference was statistically significant(χ2=4.374,P=0.036).After treatment,the clinical indexe of the study group was better than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the level of inflammatory factors in the study group was better than that in the control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of pa-tients with moderate Alzheimer's disease,memantine hydrochloride combined with cabalatine bitartrate can improve clinical efficacy,optimize clinical indicators and alleviate inflammation.

Moderate alzheimer's diseaseMemantine hydrochlorideCabalatine bitartrate

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大连市金州区第四人民医院精神科二疗区,辽宁大连 116100

中度阿尔茨海默病 盐酸美金 重酒石酸卡巴拉汀

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(5)
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