Effect of Percutaneous Renal Artery Desympathization on Cardiac Func-tion in Patients With Heart Failure With Preserved Ejection Fraction
Objective To explore the impact of percutaneous renal artery sympathetic denervation on cardiac function in heart failure patients with preserved ejection fraction.Methods A total of 68 patients with heart failure with pre-served ejection fraction admitted to Hanyuan County People's Hospital from August 2022 to December 2023 were se-lected as the study objects and divided into two groups according to the random number table method.The control group(n=34)was treated with standard anti-heart failure drugs,and the observation group(n=34)was treated with per-cutaneous renal artery sympathetic denervation.Cardiac function indexes,6-minute walking test(6 MWT)distance,serum N-terminal pro-brain natriuretic peptide level,incidence of major adverse cardiovascular events and rehospital-ization rate were compared between the two groups.Results After treatment,the left ventricular ejection fraction level and 6 MWT distance in the observation group were higher than those in the control group,and the left ventricular end-systolic diameter,left ventricular end-diastolic diameter and serum N-terminal brain natriuretic peptide precursor level were lower than those in the control group,the differences were statistically significant(all P<0.05).The inci-dence of adverse cardiovascular events(5.88%)and rehospitalization rate(14.71%)in the observation group were lower than those in the control group,the differences were statistically significant(χ2=4.221,4.826,both P<0.05).Conclusion Percutaneous renal artery desympathization can improve heart function and exercise tolerance in heart failure patients with preserved ejection fraction,reduce cardiovascular burden and readmission rate,and has good safety.
Heart failure with chronic ejection fraction retentionPercutaneous renal artery desympathizationCardiac function
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