Clinical Value of Serum Troponin(cTnI),Myoglobin(MB)and Creatine Kinase Isoenzyme(CK-MB)Combined Detection in Early Diagnosis of Acute Myocardial Infarction
Objective To explore the value of cardiac troponin I(cTnI),myoglobin(Mb)and creatine kinase isoenzyme-MB(CK-MB)combined detection in early diagnosis of acute myocardial infarction.Methods 60 patients with acute myocardial infarction in the outpatient clinic of the Second People's Hospital of Kunshan City and 60 healthy medical checkups were selected from January 2021 to December 2022,and were set up as the observation group and the control group,and were examined for cTnI,Mb,CK-MB,and analyzed the diagnostic efficacy of com-bined testing and single index testing,and compare the difference between the two groups,and analyze the diagnostic efficacy of combined detection and single index detection.Results The cTnI[(24.85±1.63)μg/mL],Mb[(122.46±18.62)μg/L]and CK-MB[(42.54±8.29)U/L]in observation group were higher than those in control group,the differ-ences were statistically significant(t=114.186,38.386,36.493,all P<0.05).The diagnostic accuracy and sensitivity of combined detection were 95.83%and 96.67%,higher than that of cTnI,Mb and CK-MB alone,the differences were statistically significant(all P>0.05).The specificity of 95.00%was not significantly different from that of single detec-tion(all P>0.05).Conclusion CTnI,Mb and CK-MB were abnormally elevated in patients with acute myocardial in-farction,and the combination of these three indexes could improve the diagnostic efficiency.