Clinical Analysis of Efficacy and Safety of Rabeprazole Combined with Ito-pride in the Treatment of Functional Dyspepsia
Objective To study the efficacy and safety of rabeprazole combined with itopride in the treatment of func-tional dyspepsia.Methods A total of 90 patients with functional dyspepsia admitted to the Affiliated Hospital of Xiangyang Vocational and Technical College from January 2021 to December 2021 were selected as the study objects,and the patients were divided into two groups with 45 cases in each group by touch ball method.The study group was treated with rabeprazole combined with itopride,the reference group was treated with itopride.The therapeutic effect,symptom score,gastrointestinal hormone,adverse reaction and recurrence rate were compared between the two groups of patients.Results The effective rate of the study group was 97.78%,higher than that of the reference group(84.44%),and the difference was statistically significant(χ2=4.939,P<0.05).After treatment,the symptom score of the study group was lower than that of the reference group,the gastrointestinal hormone index was better than that of the reference group,and the recurrence rate was significantly lower than that of the reference group,and the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions be-tween the two groups(P>0.05).Conclusion The treatment of rabeprazole combined with itopride in patients with func-tional dyspepsia can improve the therapeutic effect,alleviate clinical symptoms,improve gastrointestinal hormone lev-els,and contribute to the guarantee of safety,which also has a positive impact on the reduction of recurrence rate.
NETL
NSTL
万方数据
维普
