首页|对呼吸窘迫综合征早产儿进行经鼻间歇正压通气治疗的疗效分析

对呼吸窘迫综合征早产儿进行经鼻间歇正压通气治疗的疗效分析

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目的 评估呼吸窘迫综合征(Respiratory Distress Syndrome,RDS)早产儿接受经鼻间歇正压通气(Nasal Intermittent Positive Pressure Ventilation,NIPPV)治疗的效果.方法 回顾性选取桓台县妇幼保健院于2020年9月—2022年9月收治的71例RDS早产儿的临床资料,参照治疗方法划分对照组[纳入36例,给予经鼻持续气道正压通气(Nasal Continuous Positive Airway Pressure,NCPAP)]和观察组(纳入35例,给予NIPPV),比较两组血二氧化碳分压(Arterial Carbon Dioxide Pressure,PaCO2)、动脉血氧分压(Arterial Partial Oxygen Pressure,PaO2)、酸碱度(Pondus Hydrogenii,pH)、治疗情况、并发症发生率.结果 治疗后,观察组PaCO2低于对照组,PaO2、pH高于对照组,差异有统计学意义(P均<0.05).观察组氧疗时间为(73.53±6.71)h,短于对照组的(84.35±7.73)h,差异有统计学意义(t=6.291,P<0.05).观察组有创通气率、PS使用率低于对照组,差异有统计学意义(P均<0.05).观察组并发症发生率为 5.71%,低于对照组的 25.00%,差异有统计学意义(P<0.05).结论 对RDS早产儿实施NIPPV,可以改善血气分析结果,降低有创通气率、PS使用率,减少并发症,缩短氧疗时间.
Effect of Nasal Intermittent Positive Pressure Ventilation on Premature In-fants with Respiratory Distress Syndrome
Objective To evaluate the effects of nasal intermittent positive pressure ventilation(NIPPV)on premature infants with respiratory distress syndrome(RDS).Methods Clinical data of 71 premature infants with RDS admitted to Huantai County Maternal and Child Health Hospital from September 2020 to September 2022 were retrospectively se-lected,and divided into the control group[36 cases were included,Nasal Continuous Positive Airway Pressure(NCPAP)]and observation group(including 35 cases,given NIPPV)according to treatment methods.The Arterial Car-bon Dioxide Pressure(PaCO2),Arterial Partial Oxygen Pressure(PaCO2),Pondus Hydrogenii(pH),treatment status,complication rate were compared between the two groups.Results After treatment,PaCO2 in observation group was lower than control group,PaO2 and pH were higher than control group,the differences were statistically significant(all P<0.05).The oxygen therapy time in the observation group was(73.53±6.71)h,which was shorter than that in the con-trol group(84.35±7.73)h,and the difference was statistically significant(t=6.291,P<0.05).Invasive ventilation rate and PS utilization rate in observation group were lower than those in control group,and the differences were statisti-cally significant(both P<0.05).The incidence of complications in the observation group was 5.71%,lower than that in the control group(25.00%),and the difference was statistically significant(P<0.05).Conclusion Applying NIPPV to premature infants with RDS can improve blood gas analysis results,reduce invasive ventilation rate,PS utilization rate,reduce complications and shorten oxygen therapy time.

Premature infantsRespiratory distress syndromeBlood gas analysisComplicationsNasal intermittent positive pressure ventilation

吕璐璐、周永鑫、王福真

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桓台县妇幼保健院新生儿科,山东淄博 256400

早产儿 呼吸窘迫综合征 血气分析 并发症 经鼻间歇正压通气

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(6)
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