Effect of Nasal Intermittent Positive Pressure Ventilation on Premature In-fants with Respiratory Distress Syndrome
Objective To evaluate the effects of nasal intermittent positive pressure ventilation(NIPPV)on premature infants with respiratory distress syndrome(RDS).Methods Clinical data of 71 premature infants with RDS admitted to Huantai County Maternal and Child Health Hospital from September 2020 to September 2022 were retrospectively se-lected,and divided into the control group[36 cases were included,Nasal Continuous Positive Airway Pressure(NCPAP)]and observation group(including 35 cases,given NIPPV)according to treatment methods.The Arterial Car-bon Dioxide Pressure(PaCO2),Arterial Partial Oxygen Pressure(PaCO2),Pondus Hydrogenii(pH),treatment status,complication rate were compared between the two groups.Results After treatment,PaCO2 in observation group was lower than control group,PaO2 and pH were higher than control group,the differences were statistically significant(all P<0.05).The oxygen therapy time in the observation group was(73.53±6.71)h,which was shorter than that in the con-trol group(84.35±7.73)h,and the difference was statistically significant(t=6.291,P<0.05).Invasive ventilation rate and PS utilization rate in observation group were lower than those in control group,and the differences were statisti-cally significant(both P<0.05).The incidence of complications in the observation group was 5.71%,lower than that in the control group(25.00%),and the difference was statistically significant(P<0.05).Conclusion Applying NIPPV to premature infants with RDS can improve blood gas analysis results,reduce invasive ventilation rate,PS utilization rate,reduce complications and shorten oxygen therapy time.
Premature infantsRespiratory distress syndromeBlood gas analysisComplicationsNasal intermittent positive pressure ventilation