Comparison of Lymphocyte Subsets in Peripheral Blood of Children with Respiratory Tract Infection with Different Pathogens
Objective To analyze the difference of lymphocyte subsets of peripheral blood detected with different pathogens in children with respiratory tract infection.Methods A total of 120 children with respiratory tract infection admitted to Yixing People's Hospital from June 2022 to June 2023 were included in the observation group,including 60 children with H1N1 influenza and 60 children with mycoplasma pneumonia,and 60 healthy children who under-went physical examination during the same period were included in the control group.The detection results of periph-eral blood lymphocyte subsets in the observation group and the control group were compared,and the differences of various lymphocyte subsets in children with different pathogens were further compared.Results CD3+(907.48±11.15)%,CD3+CD8+(254.94±10.13)%,CD3-CD19+(89.51±5.22)%and CD3-CD56/16+(98.85±10.20)%of chil-dren with respiratory tract infection in observation group were significantly lower than those in control group,and CD3-CD4+(2 307.48±12.29)%was higher than that of control group,and the differences were statistically significant(t=123.749,177.729,51.590,43.580,765.587,all P<0.05).Combined with the detection results of different pathogen types in the observation group,the results showed that CD3+,CD3+CD8+,CD3-CD19+ and CD3-CD56/16+ of the chil-dren with influenza A(virus infection)were lower than those with mycoplasma pneumonia(bacterial infection),and CD3-CD4+ was higher than that with mycoplasma pneumonia,and the differences were statistically significant(all P<0.05).Conclusion There are obvious differences in the determination results of peripheral blood lymphocyte subsets caused by different pathogens in children with respiratory tract infection.Clinically,this index can be used to grasp the immune status of children and determine the type of infection,so as to provide evidence for further treatment.
NETL
NSTL
万方数据
维普
