Results of Clinical Examination of Pathogenic Bacteria in Elderly Patients with Respiratory Tract Infection
Objective To investigate and analyze the distribution of pathogenic bacteria in elderly patients with respi-ratory tract infection and analyze the results of drug sensitivity test.Methods A total of 200 elderly patients with respi-ratory tract infection admitted to Xuzhou Hospital of Traditional Chinese Medicine from January 2021 to March 2023 were selected as the study objects,and sputum samples of patients were collected in strict accordance with the operat-ing procedures for bacterial isolation and culture.The distribution of pathogenic bacteria in patients was detected,and the drug resistance was determined.Results The sputum samples of 200 elderly patients were cultured with patho-genic bacteria,and a total of 120 strains(strains repeatedly isolated from the same sample)were isolated.There were 24 patients with double or multiple pathogenic bacteria infection.The detection rate of Gram-negative bacteria(85.00%)was significantly higher than that of Gram-positive bacteria(12.50%)and fungi(2.50%).The detection rate of ESBLS-producing bacteria was 20.00%.The resistance rates of ampicillin,ceftriaxone,and cefotaxime to Klebsiella pneumoniae,Pseudomonas aeruginosa,and Acinetobacter baumannii are all above 50%;The resistance rates of imipe-nem,meropenem,and piperacillin/tazobactam to Klebsiella pneumoniae,Pseudomonas aeruginosa,and Acinetobacter baumannii are all below 30.00%.The drug resistance rates of Pseudomonas aeruginosa and Acinetobacter baumannii were below 20%to ceftazidime,ciprofloxacin,cefepime and levofloxacin respectively.The resistance rate of Staphylo-coccus aureus to penicillin and erythromycin was 75.00%,and the resistance rate to vancomycin and teicoplanin was 0.The resistance rate of ESBLS-producing strains to cephalosporin,levofloxacin,tobramycin,ampicillin was more than 50%,and the resistance rate to imipenem was 0.Conclusion The pathogenic bacteria detected in elderly pa-tients with respiratory tract infection were mainly Gram-negative bacilli,which had a certain resistance to common an-tibiotics,and the resistance rate of ESBLS-producing strains to imipenem was 0,which could provide evidence for clinical treatment.
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