Diagnostic Value of Early Acute Myocardial Infarction by Combined De-tection of Mb,cTnⅠ,CK-MB,and BNP
Objective To investigate the value of combined detection of myoglobin(Mb),troponin(cTnI),creatine ki-nase isoenzyme(CK-MB)and brain natriuretic peptide(BNP)in the diagnosis of early acute myocardial infarction.Methods A total of 100 patients with early acute myocardial infarction admitted to the hospital from January 2020 to December 2022 and 100 healthy medical checkups were selected as the infarction group and the healthy group respec-tively,and the levels of Mb,cTnI,CK-MB,and BNP were detected in both groups to compare the differences in the values between the two groups,and the diagnostic efficacy of the combined test for acute myocardial infarction was evaluated according to the clinical results.Results Mb(92.84±22.52)ng/mL,cTnI(4.96±0.78)ng/mL,CK-MB(48.91±14.62)U/L,and BNP(1 510.71±268.40)pg/mL in the infarction group were higher than those in the healthy group,and the differences were statistically significant(t=26.425,63.200,22.761,54.726,all P<0.05).The diagnostic accuracy of 95.50%and sensitivity of 96.00%of the combined test were higher than the value of the test alone,and the differences were statistically significant(all P<0.05).The specificity of the combined test was 95.00%,which was not significantly different from the test alone,and the differences were not statistically significant all(all P>0.05).Conclusion The levels of Mb,cTnI,CK-MB and BNP were obviously abnormal in patients with early acute infarction,and the combined detection of these four indexes can improve the diagnostic efficacy.
NETL
NSTL
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