Diagnostic Value of Combined Detection of Serum PCT,WBC and CRP in Neonatal Sepsis
Objective To analyze the value of serum procalcitonin(PCT),white blood cell(WBC)and C-reactive pro-tein(CRP)combined test in the diagnosis of neonatal sepsis.Methods A total of 86 children with sepsis admitted to Laibin People's Hospital from January 2021 to June 2023 were set as the observation group,and 75 healthy newborns who gave birth in the hospital during the same period were set as the health group.The difference of PCT,WBC and CRP between the two groups was compared,and the value of PCT,WBC and CRP in diagnosing neonatal sepsis was analyzed.Results In the observation group,PCT,WBC and CRP were(5.71±0.89)ng/mL,(25.88±3.61)×109/L and(15.63±2.11)mg/L respectively,higher than those in the health group[(0.24±0.03)ng/mL,(4.36±0.97)×109/L and(3.89±0.64)mg/L],and the differences were statistically significant(t=53.179,50.056,46.346,all P<0.001).The re-sults of the receiver operating characteristic curve showed that the area under curve of the combined test of neonatal sepsis by PCT,WBC and CRP was 0.934(95%CI=0.886~0.983),higher than 0.867(95%CI=0.809~0.926),0.898(95%CI=0.878~0.974)and 0.860(95%CI=0.793~0.927)of the 3 test alone.Conclusion PCT,WBC and CRP levels are high in the body of neonatal sepsis children,and the combination of the 3 test can provide a strong basis in diag-nosing neonatal sepsis.
SepsisNewbornProcalcitoninWhite blood cellC-reactive protein