Efficacy and safety of nasal continuous positive ventilation in the treatment of neonatal respiratory failure
Objective To investigate the effects of nasal continuous positive ventilation(N-CPAP)on ventilation func-tion and prognostic quality of neonatal respiratory failure.Methods A total of 90 children with respiratory failure ad-mitted to the Neonatology Department of Tengzhou Maternal and Child Health Hospital from July 2020 to July 2023 were selected as the study objects.They were divided into two groups based on different treatment plans,with 45 cases in each group.The control group was treated with conventional mechanical ventilation(CMV)and the matched group was treated with N-CPAP.The treatment effect,the relevant indexes and the occurrence of adverse events in the two groups were compared.Results The total effective rate of the matched group was 95.56%,which was higher than 80.00%of the control group,the difference was statistically significant(χ2=5.075,P<0.05).After treatment,the levels of arterial partial pressure of oxygen,oxygenation index,arterial partial pressure of oxygen/fraction of inspiration oxygen and arterial oxygen pressure/A-aDO2 were higher than those before treatment,while the levels of arterial par-tial pressure of carbon dioxide,respiratory index and brain natriuretic peptide were lower than those before treatment,and the study group had better levels,the differences were statistically significant(all P<0.05).The incidence of neo-natal adverse events in the study group was lower than that in the control group,the difference was statistically signifi-cant(P<0.05).Conclusion N-CPAP can effectively improve the ventilation function of children,and has high applica-tion value in the treatment of neonatal respiratory failure.
N-CPAPNeonatalRespiratory failureBlood gas indexBNP
NETL
NSTL
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