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乌司他丁联合奥曲肽治疗急性胰腺炎的临床效果分析

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目的 探究在对急性胰腺炎实施治疗时,采用乌司他丁+奥曲肽治疗的临床效果.方法 选取2021年12月—2023年12月贵州省三穗县中医医院收治的80例急性胰腺炎患者作为研究对象,以随机数表法分为对比组(40例)和探究组(40例).对比组以奥曲肽治疗为主,而探究组则在此基础上联用乌司他丁,对比两组症状缓解时间、疼痛程度、不良反应发生情况以及疗效.结果 探究组治疗总有效率为95.00%,相比对比组的80.00%更高,差异有统计学意义(χ2=4.114,P<0.05).相比对比组症状缓解时间,探究组腹胀缓解时间(4.68±0.53)d、腹痛缓解时间(4.24±0.43)d、肠鸣音恢复正常时间(2.41±0.68)d更短,差异有统计学意义(P均<0.05).治疗后探究组数字评分量表评分低于对比组,差异有统计学意义(P<0.05).两组不良反应发生率对比,差异无统计学意义(P>0.05).结论 在对急性胰腺炎患者实施治疗时,采用乌司他丁+奥曲肽的临床治疗效果更佳,可有效促进患者症状的缓解,并且疗效更高,具有一定的安全性.
Clinical Effect Analysis of Urinastatin Combined with Octreotide in the Treatment of Acute Pancreatitis
Objective To investigate the clinical effect of treatment with urinastatin+octreotide in the implementation of treatment for acute pancreatitis.Methods A total of 80 patients with acute pancreatitis were selected as study ob-jects from Sansui County Hospital of traditional Chinese medicine from December 2021 to December 2023.They were randomly divided into comparison group(n=40)and investigation group(n=40).The comparison group was treated with octreotide,while the investigation group was treated with ulinastatin on the basis of octreotide.The time of symp-tom relief,pain degree,adverse reaction and curative effect were compared between the two groups.Results The total effective rate of 95.00%in the investigation group was higher than that of 80.00%in the comparison group,and the difference was statistically significant(χ2=4.114,P<0.05).Compared with the symptomatic relief time of the compari-son group,the time for abdominal distension to be relieved(4.68±0.53)d,abdominal pain to be relieved(4.24±0.43)d,and bowel sounds to return to normal(2.41±0.68)d in the investigation group was shorter,and the differences were sta-tistically significant(all P<0.05).The Numerrical Rating Scale score of the investigation group was lower than that of the comparison group after treatment,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion In the implementation of the treatment of acute pancreatitis patients,the use of urinastatin+octreotide clinical treatment is more effective,can effectively promote the relief of patients'symptoms,and the efficacy is higher,with a certain degree of safety.

Acute pancreatitisUrinastatinOctreotide

刘军、任冬冬、杨文刚

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贵州省三穗县中医医院外一科,贵州三穗 556500

贵州省三穗县中医医院外一肛肠科,贵州三穗 556500

急性胰腺炎 乌司他丁 奥曲肽

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(8)