Effects of Ipratropium Bromide Combined with Budesonide Aerosol Inha-lation on Inflammatory Factors in Children with Pneumonia
Objective To explore the effects of atomized inhalation of ipratropium bromide combined with budesonide on inflammatory factors in children with pneumonia.Methods A total of 86 children with pneumonia admitted to Tai-zhou Second People's Hospital from January 2022 to September 2023 were selected as the study objects and divided into observation group and control group by random number table method,with 43 cases in each group.The observa-tion group was treated with ipratropium bromide combined with budesonide aerosol inhalation,and the control group was treated with budesonide aerosol inhalation.The indexes of lung function,myocardial enzyme profile and inflamma-tory factors were compared between the two groups.Results After treatment,forced expiratory volume in one second and peak expiratory flow indexes in observation group were(1.58±0.09)L and(2.68±0.71)L/s,respectively,higher than those in control group,and the differences were statistically significant(t=26.793,6.024,both P<0.05).After treatment,the levels of myocardial enzymes in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).After treatment,the levels of various inflammatory factors in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Combined medication can improve the symptoms of pneumonia in children and reduce the inflam-matory response of the body.
万方数据
维普
