Objective To explore the clinical effect of carprost triol injection+oxytocin injection in high-risk preg-nancy postpartum hemorrhage patients.Methods A total of 80 patients with postpartum hemorrhage during high-risk pregnancy admitted to Yanzhou District People's Hospital from February 2021 to April 2023 were selected as the study objects and divided into two groups with 40 cases each by coin throwing method.The reference group was treated with oxytocin injection,and the study group was treated with caprost triol injection+oxytocin injection.The blood loss at 2 h and 24 h after delivery,the total incidence of adverse reactions and the level of coagulation index were compared between the two groups.Results The postpartum blood loss at 2 h and 24 h in the study group were less than those in the reference group,and the differences were statistically significant(both P<0.05).The total inci-dence of adverse reactions(hypothermia,nausea,vomiting and hypertension)in the study group(7.50%)was lower than that in the reference group(27.50%),and the difference was statistically significant(χ2=5.541,P<0.05).Before treatment,there was no statistically significant difference in the levels of prothrombin time(PT),activated partial thromboplastin time(APTT),D-dimer(D-D),and fibrinogen(Fbg)between the two groups(all P>0.05).After treat-ment,the levels of PT,APTT,D-D and Fbg in the study group were better than those in the reference group,and the differences were statistically significant(all P<0.05).Conclusion Clinical treatment with carprost triol injection+oxy-tocin injection for patients with postpartum hemorrhage in high-risk pregnancies can significantly reduce the amount of postpartum blood loss at 2 h and 24 h,reduce the incidence of adverse reactions,and effectively improve the level of coagulation indicators.
关键词
卡前列素氨丁三醇注射液/缩宫素注射液/高危妊娠产后出血/产后出血量/不良反应/凝血指标
Key words
Carprost triol injection/Oxytocin injection/Postpartum hemorrhage of high-risk pregnancy/Postpartum blood loss/Adverse reactions/Coagulation index
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