首页|不同急诊溶栓药物治疗急性心肌梗死的临床效果分析

不同急诊溶栓药物治疗急性心肌梗死的临床效果分析

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目的 观察临床治疗急性心肌梗死中,不同急诊溶栓药物的实际效果.方法 选取2021年3月—2023年11月单县中心医院收治的70例急性心肌梗死患者作为研究对象,根据随机数表法分为两组,各35例.对照组采用尿激酶治疗,观察组采用重组人尿激酶原治疗,比较两组患者的心功能指标、不良反应发生率以及临床疗效.结果 治疗后,观察组左心室舒张末期内径(34.55±3.25)mm、左心室射血分数(67.02±3.56)%、6 min试验(660.21±70.45)m、B型钠尿肽(80.34±5.23)ng/L的改善状况均优于对照组,差异有统计学意义(t=33.814、34.054、18.921、22.802,P均<0.05);观察组临床疗效优于对照组,不良反应发生率低于对照组,差异有统计学意义(P均<0.05).结论 急性心肌梗死患者应用重组人尿激酶原的治疗效果良好,能够显著改善患者的生活质量.
Analysis of the Clinical Effects of Different Emergency Thrombolytic Drugs in the Treatment of Acute Myocardial Infarction
Objective To observe the effect of different emergency thrombolytic drugs in the clinical treatment of acute myocardial infarction.Methods A total of 70 patients with acute myocardial infarction admitted to Shanxian Central Hospital from March 2021 to November 2023 were selected as the study objects and divided into two groups according to random number table method,with 35 patients in each group.The control group was treated with uroki-nase,and the observation group was treated with recombinant pro-urokinase(rhPro-UK).The cardiac function in-dexes,incidence of adverse reactions and clinical efficacy of the two groups were compared.Results After treatment,left ventricular end-diastolic diameter(34.55±3.25)mm,left ventricular ejection fraction(67.02±3.56)%,6-min test(660.21±70.45)m,B-type natriuretic peptide(80.34±5.23)ng/L in the observation group were better than those in the control group,and the differences were statistically significant(t=33.814,34.054,18.921,22.802,all P<0.05).The clinical efficacy of the observation group was better than that of the control group,and the incidence of adverse reac-tions was lower than that of the control group,and the differences were statistically significant(both P<0.05).Conclu-sion Patients with acute myocardial infarction were treated well with rhPro-UK,which could significantly improve their quality of life.

UrokinaserhPro-UKAcute myocardial infarctionAdverse reactions

刘庆福、赵锤、李萍

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单县中心医院急诊科,山东菏泽 274300

尿激酶 重组人尿激酶原 急性心肌梗死 不良反应

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(9)