Exploring the Efficacy and Safety of Clopidogrel and Ticagrelor in the Treatment of Acute Myocardial Infarction
Objective To analyze the value of ticagrelor and clopidogrel in the treatment of acute myocardial infarc-tion.Methods A total of 160 patients with acute myocardial infarction admitted to Shanghe County People's Hospital from October 2020 to October 2023 were selected as the research objects,and were divided into comparison group and exploration group with 80 cases each according to the odd and even number.Clopidogrel was treated in the compari-son group,and ticagrelor was treated in the exploratory group.The platelet status,cardiac function,efficacy and safety of the two groups were compared.Results After treatment,the platelet aggregation rate and platelet count in the explo-ration group were lower than those in the comparison group,and the differences were statistically significant(both P<0.05).The left ventricular ejection fraction in the exploratory group was higher than those in the comparison group,and the left ventricular end diastolic diameter in the exploratory group was lower than that in the comparison group,and the differences were statistically significant(both P<0.05).The exploratory rate of the exploratory group was 98.75%,higher than that of the comparison group(91.25%),and the difference was statistically significan(P<0.05).The incidence of complications in the exploratory group(2.50%)was lower than that in the comparison group(11.25%),and the difference was statistically significant(χ2=4.783,P<0.05).Conclusion Ticagrelor has good curative effect,can regulate platelet status,repair heart function,has fewer complications than clopidogrel,and can reduce the risk of acute myocardial infarction.
万方数据
维普
