Clinical Efficacy of Methylprednisolone Combined with Erythromycin in the Treatment of Mycoplasma Pneumoniae Lobar Pneumonia in Children
Objective To investigate the clinical effect of methylprednisolone combined with erythromycin in the treat-ment of mycoplasma pneumoniae lobar pneumonia in children.Methods A total of 100 children with mycoplasma lo-bar pneumonia admitted to Lianshui County People's Hospital from November 2021 to November 2023 were selected as the study objects and divided into two groups by random number table method:control group(n=50)was treated with erythromycin;observation group(n=50)was treated with methylprednisolone.The clinical efficacy,symptom im-provement time,lung function and inflammatory response before and after treatment were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group(96.00%vs 82.00%),and the difference was statistically significant(χ2=5.005,P<0.05).The improvement time of symptoms in the observation group[fever(2.52±0.74)d,cough(6.50±1.22)d and pulmonary rales(5.95±1.26)d]were shorter than those in the control group,and the differences were statistically significant(t=7.126,4.836,5.050,all P<0.05).After treat-ment,the forced vital capacity,forced expiratory volume in the first second and peak expiratory flow rate in the obser-vation group were better than those in the control group,and the levels of C-reactive protein and interleukin-6 were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Eryth-romycin combined with methylprednisolone in the treatment of mycoplasma pneumoniae lobar pneumonia in children can improve the curative effect,accelerate recovery,improve lung function and reduce inflammation.
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