首页|布地奈德雾化吸入联合红霉素对支原体肺炎患儿疗效及症状改善的影响

布地奈德雾化吸入联合红霉素对支原体肺炎患儿疗效及症状改善的影响

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目的 探究布地奈德联合红霉素治疗支原体肺炎(Mycoplasma Pneumoniae Pneumonia,MPP)的价值.方法 选取2022年8月—2023年8月南京市浦口区中医院收治的108例MPP患儿为研究对象,以随机数表法分为对照组和观察组,各54例.对照组给予红霉素治疗,观察组给予布地奈德联合红霉素治疗.对比两组临床疗效、症状改善时间及住院时间、血常规指标及血清C反应蛋白水平.结果 观察组治疗总有效率(96.30%)高于对照组(85.19%),差异有统计学意义(χ2=3.967,P<0.05).观察组症状改善时间及住院时间、血常规指标及血清C反应蛋白水平低于对照组,差异有统计学意义(P均<0.05).结论 在红霉素注射治疗基础上联合布地奈德雾化吸入可发挥药物的协同作用,从而显著改善患儿临床症状,在提高临床疗效的同时降低炎性因子对机体产生的影响,从而确保预后质量.
Effect of Budesonide Aerosol Inhalation Combined with Erythromycin on the Efficacy and Symptom Improvement of Children with Mycoplasma Pneumonia
Objective To explore the value of budesonide combined with erythromycin in the treatment of mycoplasma pneumoniae pneumonia(MPP).Methods A total of one hundred and eight children with MPP admitted to Pukou Dis-trict Traditional Chinese Medicine Hospital in Nanjing from August 2022 to August 2023 were selected as the study subjects,and were divided into control group and observation group with fifty-four cases in each group by random number table method.The control group was treated with erythromycin,and the observation group was treated with budesonide combined with erythromycin.The therapeutic effect,symptom improvement and hospitalization time,blood routine index and serum C-reactive protein level of two groups were compared.Results The total effective rate(96.30%)of the observation group was higher than that of the control group(85.19%),and the difference was statisti-cally significant(χ2=3.967,P<0.05).The time for symptom improvement and hospitalization,blood routine indicators,and serum C-reactive protein level in the observation group were lower than those in the control group,and the differ-ences were statistically significant(all P<0.05).Conclusion Combined with budesonide aerosol inhalation on the basis of erythromycin injection can play a synergistic role and significantly improve the clinical symptoms of children.It can improve the clinical efficacy and reduce the impact of inflammatory factors on the body,so as to ensure the quality of prognosis.

BudesonideErythromycinAtomization therapyMycoplasma pneumoniaMycoplasma

朱晓丽、李晓倩

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南京市浦口区中医院儿科,江苏南京 211800

布地奈德 红霉素 雾化治疗 支原体肺炎 支原体

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(9)