首页|血清降钙素原与C反应蛋白联合检测在肺炎诊断中的价值分析

血清降钙素原与C反应蛋白联合检测在肺炎诊断中的价值分析

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目的 分析血清降钙素原与C反应蛋白联合检测在肺炎诊断中的价值.方法 选取2022年10月—2023年10月东阿县高集中心卫生院收治的100例小儿肺炎患儿为观察组,并选择同期84名健康体检者为对照组,对比两组儿童血清降钙素原(Procalcitonin,PCT)和C反应蛋白(C-reactive Protein,CRP)水平,并比较血清PCT、CRP水平单独检测和两者联合检测的诊断效能.结果 观察组患儿的PCT(2.36±0.08)ng/mL、CRP(16.41±6.82)mg/L水平显著高于对照组的(0.02±0.01)ng/mL,(1.10±0.30)mg/L,差异有统计学意义(t=266.225、20.549,P均<0.05).血清PCT水平和CRP水平检测的灵敏度、准确度、特异度比较,差异无统计学意义(P均>0.05);但联合检测的灵敏度、特异度和准确度比单一检测高,差异有统计学意义(P均<0.05).结论 采用血清PCT和CRP水平联合检测肺炎的诊断价值较高.
Analysis of the Value of Combined Detection of Serum Procalcitonin and C-reactive Protein in the Diagnosis of Pneumonia
Objective To analyze the value of combined detection of serum procalcitonin and C-reactive protein in the diagnosis of pneumonia.Methods 100 children with pneumonia who were admitted to Dong'e County Gaoji Cen-tral Health Center from October 2022 to October 2023 were selected as the observation group.And 84 healthy examin-ees during the same period were selected as the control group.The serum procalcitonin(PCT)and C-reactive protein(CRP)levels of the two groups of children were compared,and the diagnostic efficacy of serum PCT and CRP alone and combined detection was compared.Results The levels of PCT(2.36±0.08)ng/mL and CRP(16.41±6.82)mg/L in observation group were significantly higher than those in control group(0.02±0.01)ng/mL,(1.10±0.30)mg/L,and the differences were statistically significant(t=266.225,20.549,both P<0.05).There was no statistically significant differ-ence in sensitivity,accuracy and specificity between serum PCT level and CRP level(all P>0.05).However,the sensi-tivity,specificity and accuracy of combined detection were higher than those of single detection,and the differences were statistically significant(all P<0.05).Conclusion The combined detection of serum PCT and CRP levels is of high diagnostic value for pneumonia.

Serum procalcitoninC-reactive proteinPneumoniaDiagnosis

孙玉霞、邓法文、周淑霞

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东阿县高集中心卫生院检验科,山东聊城 252200

东阿县人民医院感染性疾病科,山东聊城 252200

东阿县陈集镇卫生院检验科,山东聊城 252200

血清降钙素原 C反应蛋白 肺炎 诊断

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(9)