Effect of Dipyridamole on T Lymphocyte Subsets and Coagulation Func-tion in Children with Kawasaki Disease
Objective To investigate the clinical effect of dipyridamole adjuvant therapy on children with Kawasaki disease,and observe the effect on coagulation function and T lymphocyte subsets.Methods A total of 130 children with Kawasaki disease in Wuxi Children's Hospital during the period from February 2021 to May 2022 were selected as the study objects.All children were grouped with reference group and study group according to the coin toss method,and with 65 cases in each group.The reference group received conventional treatment,and study group re-ceived dipyridamole adjuvant therapy.The total effective rate,the level of coagulation function index,the level of T lymphocyte subsets and the duration of clinical symptom remission were compared between the two groups.Results The total effective rate of the study group(98.46%)was higher than that of the reference group(87.69%),and the dif-ference was statistically significant(χ2=5.849,P<0.05).After treatment,compared with the reference group,the levels of FIB in the study group was significantly decreased,while the levels of APTT and PT were significantly increased,and the differences were statistically significant(all P<0.05).Conclusion After completing adjuvant therapy with di-pyridamole in children with Kawasaki disease,the therapeutic effect of the children can be improved,the level of co-agulation function indicators and T lymphocyte subsets can be significantly improved,and the duration of clinical symptom remission can be significantly shortened.
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