罗哌卡因与小剂量艾司氯胺酮联合应用在硬膜外分娩镇痛中对产妇的影响研究
Effect of Combination of Ropivacaine and Low Dose Esketamine on Partu-rients during Epidural Labor Analgesia
李继成 1刘丹丹 1周海峰 1骆习珍 1李泽龙1
作者信息
- 1. 孝感市妇幼保健院麻醉科,湖北孝感 432100
- 折叠
摘要
目的 探讨罗哌卡因与小剂量艾司氯胺酮联合应用在硬膜外分娩镇痛中对产妇的影响.方法 回顾性分析2023年1-12月在孝感市妇幼保健院接受硬膜外分娩镇痛的160例产妇的临床资料,以不同镇痛方式分为两组,每组80例.传统组应用舒芬太尼+罗哌卡因,探究组应用小剂量艾司氯胺酮+罗哌卡因.对比两组麻醉相关时间、生命体征水平及不良反应发生率.结果 探究组麻醉起效时间(1.35±0.26)min短于传统组(2.41±0.33)min,麻醉维持时间(63.27±6.16)min长于传统组(57.25±5.12)min,差异有统计学意义(t=22.567、6.722,P均<0.05).与传统组相比,探究组生命体征水平更稳定,差异有统计学意义(P<0.05).探究组不良反应发生率略高于传统组,但差异无统计学意义(P>0.05).结论 罗哌卡因与小剂量艾司氯胺酮联合应用在硬膜外分娩镇痛中,能够显著缩短麻醉起效时间,延长麻醉维持时间,提高产妇生命体征的稳定性,并且不增加不良反应发生率.
Abstract
Objective To investigate the effect of combination of ropivacaine and low dose esketamine on parturients during epidural labor analgesia.Methods Clinical data of 160 parturients who received epidural labor analgesia in Xiaogan Maternal and Child Health Hospital from January to December 2023 were retrospectively analysed and di-vided into two groups based on different analgesia methods,with eighty cases in each group.The traditional group re-ceived sufentanil+ropivacaine,and the exploratory group received low dose esketamine+ropivacaine.Anesthesia re-lated time,vital signs level and incidence of adverse reactions were compared between the two groups.Results The on-set time of anesthesia in the exploratory group(1.35±0.26)min was shorter than that in the traditional group(2.41±0.33)min,and the maintenance time of anesthesia(63.27±6.16)min was longer than that in the traditional group(57.25±5.12)min,and the differences were statistically significant(t=22.567,6.722,both P<0.05).Compared with the traditional group,the level of vital signs in the exploratory group was more stable,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the exploratory group was slightly higher than that in the traditional group,but the difference was not statistically significant(P>0.05).Conclusion The combined application of ropivacaine and low-dose esketamine in epidural labor analgesia can significantly shorten the onset time of anesthe-sia,prolong the maintenance time of anesthesia,improve the stability of maternal vital signs,and do not increase the incidence of adverse reactions.
关键词
罗哌卡因/艾司氯胺酮/硬膜外分娩镇痛/产妇/生命体征Key words
Ropivacaine/Esketamine/Epidural labor analgesia/Puerpera/Vital signs引用本文复制引用
基金项目
孝感市自然科学计划拟立项项目(XGKJ2023010029)
出版年
2024
NETL
NSTL
万方数据