Application Value of Total Bilirubin,Albumin,Total Bile Acid and Cholin-esterase in the Diagnosis of Esophageal Varices with Cirrhosis
Objective To investigate the application value of total bilirubin,albumin,total bile acid and cholinester-ase in patients with liver cirrhosis complicated with esophageal and gastric varices.Methods 80 patients with cirrho-sis complicated with esophageal and gastric varices admitted to Jinsha County Hospital of Traditional Chinese Medi-cine from March to December 2022 were selected as the disease group,80 patients with simple cirrhosis admitted to hospital during the same period were selected as the simple disease group,and 80 volunteers who underwent physical examination in the hospital during the same period were selected as the control group.The indexes of total bilirubin,albumin,total bile acid and cholinesterase were compared in three groups.Subsequently,the varicose degree of pa-tients with cirrhosis complicated with esophagogastric varicose veins was graded,and the difference of serological in-dexes in different varicose veins was analyzed.Results The total bile acids in the disease group were(28.91±7.92)μmol/L,and were(9.15±4.52)μmol/L in the simple disease group,which were significantly higher than those in the control group(7.26±1.13)μmol/L,and the difference was statistically significant(F=18.885,P<0.05).The levels of cholinesterase and albumin in disease group were lower than those in simple disease group,and both disease group and simple disease group were lower than control group,the differences were statistically significant(all P<0.05).The total bilirubin in disease group was higher than that in simple disease group,and both groups were higher than control group,the difference was statistically significant(P<0.05).With the severity of the disease,the albumin and cholines-terase of the patients decreased,and the total bilirubin and total bile acid increased significantly,and the differences were statistically significant(all P<0.05).Conclusion In patients with cirrhosis complicated with esophageal and gas-tric varicose veins,the changes of the disease can be observed by measuring the indexes of total bilirubin,albumin,to-tal bile acid and cholinesterase.Compared with normal people,the total bile acid and total bilirubin are significantly increased,while albumin and cholinesterase are significantly decreased,which should be paid attention to clinically.
Liver cirrhosisSerum detectionEsophageal and gastric varicesApplication value
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