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研究缬沙坦与氢氯噻嗪联合治疗高血压心脏病的效果

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目的 分析高血压心脏病实施缬沙坦+氢氯噻嗪治疗的价值.方法 选取2022年11月—2023年11月鱼台县总医院收治的92例高血压心脏病患者作为研究对象,依据随机数表法分为普通组、研究组,各46例,普通组行缬沙坦治疗,研究组在普通组的基础上加用氢氯噻嗪.比较两组的血压、心功能指标、疗效和不良反应发生情况.结果 治疗前,两组的血压和心功能指标比较,差异无统计学意义(P均>0.05).治疗后,研究组的血压和心功能指标均优于普通组,差异有统计学意义(P均<0.05).研究组治疗总有效率(97.83%)高于普通组(82.61%),差异有统计学意义(χ2=4.434,P<0.05).研究组的不良反应发生率为4.35%,低于普通组的19.57%,差异有统计学意义(P<0.05).结论 缬沙坦+氢氯噻嗪的方案能迅速降低血压,改善心脏功能,减少不良反应,使高血压心脏病患者得到有效安全的治疗.
Study on the Effect of Combined Treatment of Hypertensive Heart Disease with Valsartan and Hydrochlorothiazide in Hypertensive Heart Disease
Objective To analyze the value of implementing valsartan+hydrochlorothiazide treatment for hyperten-sive heart disease.Methods A total of 92 patients with hypertensive heart disease admitted to Yutai County General Hospital from November 2022 to November 2023 were selected as the study objects,and were divided into general group and study group according random number table method,46 cases in each group.The general group received valsartan treatment,and the study group received hydrochlorothiazide on the basis of the general group.Blood pres-sure,cardiac function indexes,curative effect and adverse reactions were compared between the two groups.Results Before treatment,there was no significant difference in blood pressure and cardiac function between the two groups(both P>0.05).After treatment,the blood pressure and cardiac function indexes of the study group were better than those of the general group,and the differences were statistically significant(both P<0.05).The total effective rate of treatment the study group(97.83%)was higher than that of the general group(82.61%),and the difference was statisti-cally significant(χ2=4.434,P<0.05).The incidence of adverse reactions in the study group was 4.35%,lower than 19.57%in the general group,and the difference was statistically significant(P<0.05).Conclusion The regimen of val-sartan+hydrochlorothiazide can rapidly reduce blood pressure,improve cardiac function,reduce adverse reactions,so that hypertensive heart disease patients can be effectively and safely treated.

Hypertensive heart diseaseClinical efficacyValsartanCardiac functionHydrochlorothiazide

夏玉喜、马尊良

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鱼台县总医院西院区内科,山东济宁 272300

高血压心脏病 临床疗效 缬沙坦 心功能 氢氯噻嗪

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(10)