目的 分析红细胞分布宽度/白蛋白值(Red Cell Distribution Width to Albumin Ratio,RAR)、纤维蛋白原/白蛋白值(Fibrinogen to Albumin Ratio,FAR)预测慢性肾脏病(Chronic Kidney Disease,CKD)3～5期患者发生左心室肥厚(Left Ventricular Hypertrophy,LVH)的诊断价值分析.方法 回顾性选取2023年4-9月徐州医科大学附属医院收治的169例CKD3～5期患者的临床资料,其中合并LVH者77例为LVH组,无LVH者92例为非LVH组.对比两组临床资料、RAR、FAR;采用多因素Logistic回归分析发生LVH的独立危险因素;采用受试者工作特征(Receiver Operating Characteristic,ROC)曲线评价RAR、FAR对CKD3～5期的患者并发LVH诊断价值.结果 LVH组患者的RAR、FAR显著高于非LVH组,差异有统计学意义(P均＜0.05).多因素Logistic回归分析结果表明RAR、FAR升高是CKD3～5期患者并发LVH独立危险因素(P均＜0.05);RAR、FAR对CKD3～5期患者并发LVH的预测的曲线下面积分别是0.785、0.893,其最佳截断值分别为4.63%、88.82%;联合检验预测CKD3～5期患者并发LVH的曲线下面积为0.968.结论 RAR、FAR在CKD3～5期并发LVH患者中的表达明显升高,其对CKD发生LVH具有良好的预测价值.
Diagnostic Value of Red Cell Distribution Width to Albumin Ratio and Fi-brinogen to Albumin Ratio in Predicting the Occurrence of Left Ventricu-lar Hypertrophy in Patients with Chronic Kidney Disease Stages 3 to 5
Objective To analyze the diagnostic value of red cell distribution width to albumin ratio(RAR)and fi-brinogen to albumin ratio(FAR)in predicting the occurrence of left ventricular hypertrophy(LVH)in patients with chronic kidney disease(CKD)stages 3 to 5.Methods The clinical data of 169 patients with CKD stage 3～5 admitted to the Affiliated Hospital of Xuzhou Medical University from April to September 2023 were retrospectively selected,of which 77 cases with combined LVH were in the LVH group and 92 cases without LVH were in the non-LVH group.The clinical data,RAR,and FAR of the two groups were compared.Independent risk factors for the occurrence of LVH were calculated using multivariate Logistic regression analysis.The receiver operating characteristic(ROC)curve was used to evaluate the diagnostic value of RAR and FAR for the complication of LVH in patients with CKD stage 3～5.Results The RAR and FAR of patients in the LVH group were significantly higher than those in the non-LVH group,the differences were statistically significant(both P＜0.05).The results of multivariate Logistic regression analy-sis indicated that elevated RAR and FAR were independent risk factors for the complication of LVH in patients with CKD stages 3～5(both P＜0.05).The area under the curve of RAR and FAR for the prediction of concomitant LVH in patients with CKD stage 3～5 was 0.785 and 0.893,respectively,and their optimal intercept values were 4.63%and 88.82%,respectively.The area under the curve for the prediction of LVH in patients with CKD stage 3～5 by the com-bined test was 0.968.Conclusion The expression of RAR and FAR was significantly elevated in patients with CKD stage 3～5 who had LVH,and they have good predicting value for CKD combined with LVH.
Red cell distribution widthFibrinogenAlbuminChronic kidney diseaseLeft ventricular hypertrophy
NETL
NSTL
万方数据
