Value of Anti-thyroglobulin Antibody and Anti-thyroid Peroxidase Anti-body in the Diagnosis of Thyroid Dysfunction
Objective To investigate the value of anti-thyroglobulin antibodies(TgAb)and anti-thyroid peroxidase antibodies(TPOAb)in the diagnosis of thyroid dysfunction.Methods Clinical data of patients with thyroid dysfunc-tion(50 cases,observation group)and normal thyroid function(50 cases,control group)diagnosed in Guanyun County Hospital of Traditional Chinese Medicine,Jiangsu Province from January 2021 to May 2023 were retrospec-tively selected.The levels of TgAb and TPOAb in the two groups were detected and the diagnostic value was ana-lyzed.Results The levels of TgAb and TPOAb in observation group were significantly higher than those in control group,the differences were statistical significance(all P＜0.05).The levels of TgAb and TPOAb in Hashimoto's group were higher than those in the other 3 groups,and those in Graves'group were higher than those in hyperthyroidism and hypothyroidism group,and those in hyperthyroidism group were higher than those in hypothyroidism group,the differences were statistical significance(all P＜0.05).The diagnostic sensitivity,specificity and accuracy of the com-bined test were 98.00%,96.00%and 97.00%,which were higher than the diagnostic efficacy of the two antibody tests alone(all P＜0.05).Conclusion TgAb combined with TPOAb test has high applied value in the diagnosis of thy-roid dysfunction,and can be used to distinguish different types of thyroid diseases.
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