Value of Tubercle Interferon-gamma Release Assay Chemiluminescence Immunoassay in the Diagnosis of Tuberculosis
Objective To analyze the value of tubercle interferon-gamma release assay chemiluminescence immunoas-say(TB-IGRA CLIA)in the diagnosis of tuberculosis.Methods A total of 109 patients with suspected pulmonary tu-berculosis who were examined in Chuzhou Hospital of Traditional Chinese Medicine of Huai'an City,Jiangsu Province from January 2020 to April 2023 were selected as the study objects.All the subjects were subjected to tuberculin skin test and TB-IGRA CLIA.The results of acid-fast staining test were taken as the gold standard,and the application re-sults and diagnostic efficiency of the two detection methods in the diagnosis of pulmonary tuberculosis were compared.Results The number of true positive cases in tuberculosis diagnosis by TB-IGRA CLIA was more than that by tuber-culin skin test.The sensitivity(94.74%)and accuracy(93.58%)of TB-IGRA were higher than those of the tuberculin skin test(84.21%,81.65%),and the differences were statistically significant(χ2=5.588,7.144,both P<0.05).Conclu-sion In the diagnosis of tuberculosis disease,the application of TB-IGRA has high value,the diagnostic results are close to the gold standard,and the diagnostic efficiency is high.
TB-IGRA CLIATuberculosisDiagnosisTuberculin skin testAcid fast staining test