Impact of Ultra-early Thrombolysis on Successful Recanalization Rate of Thrombolysis,Adverse Cardiac Events and Quality of Life in ASTEMI Pa-tients
Objective To observe the effects of ultra-early thrombolysis on the successful recanalization rate of throm-bolysis,adverse cardiac events,and quality of life in patients with acute ST-segment elevation myocardial infarction(ASTEMI).Methods The dinical data of Seventy-eight patients with ASTEMI admitted to Zaozhuang Shizhong Dis-trict People's Hospital from January 2020 to December 2022 were retrospectively selected.According to the time from the appearance of acute myocardial infarction symptoms to thrombolytic therapy,the patients were divided into two groups:the ultra-early(＜3 h)thrombolysis group(observation group)and the non-ultra-early(3-12 h)thrombolysis group(control group),each with 39 cases.After thrombolytic treatment,the successful recanalization rate of thromboly-sis,the incidence of adverse cardiac events and the quality of life scores of patients in the two groups were compared.Results The successful recanalization rate of thrombolysis in the observation group was 82.05%,while that of the con-trol group was only 61.53%,and the difference was statistically significant(χ2=4.052,P＜0.05).The incidence rate of adverse cardiac events in the observation group was 5.13%,which was significantly lower than the 20.51%in the con-trol group,and the difference was statistically significant(χ2=4.129,P＜0.05).The scores of all dimensions of quality of life in the observation group were higher than those in the control group,and the differences were statistically sig-nificant(all P＜0.05).Conclusion The implementation of ultra-early thrombolysis improves the successful recanaliza-tion rate of thrombolysis in patients with acute ST-segment elevation myocardial infarction,reduces the incidence of adverse cardiac events,and improves the quality of life of patients.
Acute ST-segment elevation myocardial infarctionIntravenous thrombolytic therapyUltra-early thrombolysisAdverse cardiac eventsQuality of life
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