首页|甲泼尼龙琥珀酸钠对重症支原体肺炎患儿疗效与机体炎症的影响

甲泼尼龙琥珀酸钠对重症支原体肺炎患儿疗效与机体炎症的影响

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目的 分析在重症支原体肺炎(Mycoplasma Pneumonia,MPP)患儿治疗中采取甲泼尼龙琥珀酸钠治疗对其疗效与炎症反应的影响.方法 选取2019年1月—2023年6月曹县人民医院普儿一科收治的62例重症MPP患儿,以随机数表法分组,观察组31例采取甲泼尼龙琥珀酸钠治疗,对照组31例采取常规治疗,比较两组临床疗效、临床症状改善时间、炎症因子水平.结果 观察组总有效率为93.6%,高于对照组(80.6%),差异有统计学意义(χ2=7.381,P<0.05).治疗后,观察组各项症状改善时间均比对照组更短,差异有统计学意义(P均<0.05).治疗后,观察组各项炎症因子水平优于对照组,差异有统计学意义(P均<0.05).结论 对重症MPP患儿采取甲泼尼龙琥珀酸钠治疗有较高治疗效果,还可显著缩短患儿临床症状改善时间,减轻炎症状态,较常规治疗更有助于促进患儿康复.
Effect of Methylprednisolone Sodium Succinate on Therapeutic Effect and Body Inflammation in Children with Severe Mycoplasma Pneumonia
Objective To analyze the effect of methylprednisolone sodium succinate on the therapeutic effect and in-flammatory response of children with severe mycoplasma pneumonia(MPP).Methods A total of sixty-two children with severe MPP admitted to the Department of General Pediatrics I of Caoxian People's Hospital from January 2019 to June 2023 were selected.The children in the observation group(31 cases)were treated with methylprednisolone so-dium succinate,and the control group(31 cases)were treated with conventional treatment.The clinical efficacy,im-provement time of clinical symptoms and levels of inflammatory factors were compared between the two groups.Re-sults The total effective rate of the observation group was 93.6%,higher than that of the control group(80.6%),and the difference was statistically significant(χ2=7.381,P<0.05).After treatment,the improvement time of symptoms in the observation group was shorter than that in the control group,and the difference was statistically significant(all P<0.05).After treatment,the levels of various inflammatory factors in the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Methylprednisolone sodium succinate treatment for severe MPP children has a higher therapeutic effect,and can significantly shorten the improve-ment time of clinical symptoms and reduce inflammation,and is more conducive to promoting children rehabilitation than conventional treatment.

Methylprednisolone sodium succinateSevere caseMPPInflammation

孙文平、彭红梅、黄春彦

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曹县人民医院普儿科一病区,山东菏泽 274400

甲泼尼龙琥珀酸钠 重症 支原体肺炎 炎症

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(11)