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膀胱癌肿瘤标志物检测方法的应用进展研究

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膀胱癌作为泌尿系统中常见的恶性肿瘤,具有高复发率和不良预后的特性,早期诊断和有效监测对于改善患者的生存率至关重要.膀胱癌肿瘤标志物的检测方法在疾病的早期发现、治疗效果评估以及预后分析中发挥着关键作用.本文聚焦于膀胱癌肿瘤标志物的分类与检测技术的最新研究进展,涵盖多种标志物,探讨DNA电化学传感器、电化学免疫传感器(包括免标记电化学免疫传感器与三明治电化学免疫传感器)及其他检测方法(如荧光原位杂交技术和酶联免疫吸附测定法).这些方法因其高灵敏度、操作简便、无创性及低成本等优势,已经成为膀胱癌管理中不可或缺的工具.本文旨在为膀胱癌的诊断、治疗及预后提供更有效的策略.
Progress in the Application of Tumor Marker Detection Methods for Blad-der Cancer
As a common malignant tumor in the urinary system,bladder cancer has a high recurrence rate and poor prognostic characteristics.Early diagnosis and effective monitoring are crucial for improving patient survival.The de-tection methods of bladder cancer tumor markers play a key role in the early detection of the disease,the assessment of treatment effects,and the prognosis analysis.This review focused on the latest research advances in the classifica-tion and detection techniques of bladder cancer tumor markers,covering a wide range of markers,and discusses DNA electrochemical sensors,electrochemical immunosensors(including label-free electrochemical immunosensors and sandwich electrochemical immunosensors),and other detection methods(such as fluorescence in situ hybridization and enzyme-linked immunosorbent assay).These methods have become indispensable tools in the management of bladder cancer due to their high sensitivity,simplicity,non-invasiveness and low cost.The aim of this paper is to pro-vide more effective strategies for the diagnosis,treatment and prognosis of bladder cancer.

Bladder cancerTumor markersDetection methods

孟竹、席艺华、王凤

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北京市朝阳区桓兴肿瘤医院检验科,北京 100023

涿州市医院检验科,河北涿州 072750

膀胱癌 肿瘤标志物 检测方法

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(11)