Diagnostic Value of MALB,CysC and β2-MG in Early Diabetic Ne-phropathy
Objective To analyze the diagnostic value of urinary microalbumin(MALB),serum cystatin C(CysC)and β-2 microglobulin(β2-MG)in early diabetic nephropathy.Methods A total of one hundred and fifty-one healthy physical examination personnel who underwent physical examination in Xinyi People's Hospital from July 2022 to June 2023 were non-randomly selected as the control group,while one hundred and fifty-one patients with simple dia-betes were non-randomly selected as the observation group A and one hundred and fifty-one patients with early dia-betic nephropathy were non-randomly selected as the observation group B.All subjects were tested by MALB,CysC and β2-MG,and the diagnostic value of MALB,CysC,β2-MG and the combined detection of the three indexes in early diabetic nephropathy were compared.Results The CysC,β2-MG,MALB and CysC of observation group A and observation group B were higher than those of control group,and observation group B was higher than observation group A,the differences were statistically significant(all P<0.05).The specificity of MALB,CysC and β2-MG com-bined diagnosis was 95.70%,which was higher than that of single index detection(83.77%,85.76%and 83.11%),and the difference was statistically significant(χ2=27.559,P<0.05).The sensitivity and accuracy of combined diagnosis were higher than that of single index detection,and the differences were statistically significant(all P<0.05).Conclu-sion In the diagnosis of early diabetic nephropathy,the diagnostic efficacy of MALB,CysC and β2-MG combined de-tection is higher than that of each single detection.
Urinary microalbuminSerum cystatin Cβ-2 microglobulinEarly diabetic nephropathyPositive rateDiagnostic value
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