首页|基层医院终末期肾病患者不同透析方式的临床疗效研究

基层医院终末期肾病患者不同透析方式的临床疗效研究

扫码查看
目的 探讨基层医院终末期肾病(End-stage Renal Disease,ESRD)患者应用不同透析方式的治疗效果.方法 目的选取织金县人民医院于2023年1-12月收治的137例ESRD患者为研究对象,按不同透析方式分成A组(n=39)、B组(n=45)、C组(n=53).A组每周透析两次,4.5 h/次;B组每周透析两次,4 h/次;C组每周透析3次,4 h/次.对比3组营养指标、炎症指标及并发症发生情况.结果 治疗后,3组营养指标水平较治疗前提高,A组营养指标水平高于B组,差异有统计学意义(P均<0.05),而A组与C组比较,差异无统计学意义(P>0.05).治疗后,3组炎症指标水平均低于治疗前,A组项炎症指标水平优于B组,差异有统计学意义(P均<0.05),而A组与C组比较,差异无统计学意义(P>0.05).A组并发症总发生率(10.26%)低于B组(28.89%)、C组(30.19%),差异有统计学意义(χ2=5.241,P<0.05).结论 对于基层医院ESRD患者,选择每周透析两次,4.5 h/次的透析方式,总体效果优于每周2次、4 h/次的透析患者,而与每周3次,4 h/次的透析患者的治疗效果相当,但每周透析两次,4.5 h/次的透析方式可降低透析并发症的发生率.
Clinical Efficacy Studies of Different Dialysis Modalities in Patients with End-Stage Renal Disease in Primary Hospitals
Objective To investigate the therapeutic effect of different dialysis methods in patients with End-stage re-nal disease(ESRD)in primary hospital.Methods A total of 137 ESRD patients admitted to Zijin County People's Hospital from January to December 2023 were purposely selected as study objects and divided into Group A(n=39),Group B(n=45),and Group C(n=53)according to different dialysis methods.Group A was dialyzed twice a week,4.5 h/times;Group B was dialyzed twice a week,4 h/times;Group C was dialyzed three times a week,4 h/times.Nutri-tional indexes,inflammatory indexes and complications occurred in the 3 groups were compared.Results After treat-ment,the level of nutritional indicators in the 3 groups was higher than that before treatment,and the level of nutri-tional indicators in group A was higher than that in group B,and the difference was statistically significant(all P<0.05),while 3 was no statistically significant difference when comparing group A with group C(P>0.05).After treat-ment,the level of inflammatory indexes in the three groups was lower than that before treatment,and the level of in-flammatory indexes in group A was better than that in group B,and the differences were statistically significant(all P<0.05),while there was no statistically significant difference when comparing group A with group C(P>0.05).The total incidence of complications in group A(10.26%)were lower than that in group B(28.89%)and group C(30.19%),and the differences were statistically significant(χ2=5.241,P<0.05).Conclusion For ESRD patients in primary hospitals,choosing dialysis twice a week at 4.5 h/times has better overall results than dialysis patients on dialysis twice a week at 4 h/times,but comparable treatment outcomes to those on dialysis three times a week at 4 h/times,but dialysis twice a week at 4.5 h/times can reduce the incidence of dialysis complications.

End-stage renal diseaseDialysis modalityNutritional indexInflammatory indexComplications

徐国俊、徐洪、杨宇洁、杨云

展开 >

织金县人民医院肾病风湿科,贵州 织金 552100

黔东南民族职业技术学院,贵州 凯里 556000

终末期肾病 透析方式 营养指标 炎症指标 并发症

贵州省卫生健康委科学技术基金项目

gzwkj2022-328

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(12)