首页|盐酸替罗非班联合常规治疗在急性进展性脑梗死患者中的应用

盐酸替罗非班联合常规治疗在急性进展性脑梗死患者中的应用

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目的 探讨急性进展性脑梗死患者使用常规治疗与盐酸替罗非班的效果.方法 目的选取山东国欣颐养集团枣庄中心医院于2022年8月—2023年11月收治的80例急性进展性脑梗死患者为研究对象,根据不同治疗方法将其分成常规组、研究组,每组40例.常规组接受常规治疗干预,研究组接受盐酸替罗非班联合常规治疗干预,比较两组的凝血功能指标、不良反应发生率和治疗有效率.结果 治疗后,研究组治疗总有效率(97.50%)高于常规组(82.50%),差异有统计学意义(χ2=5.000,P<0.05).研究组的凝血功能指标优于常规组,差异有统计学意义(P均<0.05).研究组不良反应发生率略低于常规组,差异无统计学意义(P>0.05).结论 急性进展性脑梗死患者行常规治疗联合盐酸替罗非班治疗可显著改善凝血功能,提高临床疗效,且安全性较好.
Application of Tirofiban Hydrochloride Combined with Conventional Therapy in Patients with Acute Progressive Cerebral Infarction
Objective To investigate the effect of conventional treatment and tirofiban hydrochloride on patients with acute progressive cerebral infarction.Methods A total of 80 patients with acute progressive cerebral infarction admit-ted to Zaozhuang Central Hospital of Shandong Guoxin Yiyang Group from August 2022 to November 2023 were pur-posely selected as the study objects,and they were divided into conventional group and study group by different treat-ment modalities,with 40 cases in each group.The conventional group received conventional treatment intervention,and the study group received tirofiban hydrochloride combined with conventional treatment intervention.The index of coagulation function,incidence of adverse reactions and effective rate of treatment were compared between the two groups.Results After treatment,the total effective rate of the study group(97.50%)was higher than that of the conven-tional group(82.50%),and the difference was statistically significant(χ2=5.000,P<0.05).The coagulation function in-dex of the study group was better than that of the conventional group,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the study group was slightly lower than that in the conventional group,with no statistical significance(P>0.05).Conclusion Conventional treatment combined with tirofiban hydro-chloride in patients with acute progressive cerebral infarction can significantly improve coagulation function,improve clinical efficacy,and have good safety.

Acute progressive cerebral infarctionTirofiban hydrochlorideCoagulation functionTreatment

张盛、孙启朋、刘丙乐

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山东国欣颐养集团枣庄中心医院神经内一科,山东 枣庄 277000

山东国欣颐养集团枣庄中心医院神经内二科,山东 枣庄 277000

急性进展性脑梗死 盐酸替罗非班 凝血功能 治疗

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(12)