Clinical Effects of Cold Knife Cervical Conization on Patients with Cervi-cal Intraepithelial Neoplasia
Objective To analyze the clinical effect of cold knife cervical conization in patients with cervical intraepi-thelial neoplasia(CIN).Methods The clinical data of 20 patients with CIN admitted to Urumqi First People's Hospital from January 2021 to January 2023 were retrospectively selected,and they were divided into two groups according to the type of surgery,with 10 cases in each group.In the control group,loop electrosurgical excision procedure was per-formed,and in the observation group,cold knife cervical conization was implemented.Compared the total effective rate of treatment,general index of surgery,incidence of postoperative complications,positive incision margin rate,dis-ease recurrence rate and pregnancy rate in the two groups within 1 year after surgery.Results The total effective rate of treatment,time of vaginal discharge,time of cervical repair,incidence of postoperative complications,rate of posi-tive margins within 1 year postoperatively and disease recurrence rate in the two groups were compared,the differ-ences were not statistically significant(all P>0.05).The operation time(41.51±15.89)min and hospitalization time(5.88±1.21)d of the observation group were longer than those of the control group(15.22±5.34)min,(3.25±0.96)d,and intraoperative blood loss(44.35±16.28)mL was more than that of the control group(21.14±8.69)mL,and the dif-ferences were statistically significant(t=4.959,5.385,3.977,all P<0.05).The pregnancy rate within 1 year after the operation in the observation group(70.00%)was higher than in the control group(10.00%),the difference was statisti-cally significant(P<0.05).Conclusion Both loop electrosurgical excision procedure and cold knife cervical conization in patients with CIN can achieve relatively satisfactory near-and long-term therapeutic effects.In comparison,loop electrosurgical excision procedure has shorter treatment time and less intraoperative blood loss,but cold knife cervical conization is beneficial to protect the fertility of patients.
万方数据
维普
