首页|血清FT3、FT4、TSH单项及联合检测对临床诊断甲状腺功能减退症的效能探讨

血清FT3、FT4、TSH单项及联合检测对临床诊断甲状腺功能减退症的效能探讨

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目的 探究血清游离三碘甲状腺激素(Free Triiodothyronine,FT3)、游离甲状腺素(Free Triiodothyronine,FT4)、促甲状腺激素(Thyroid Stimulating Hormone,TSH)单项及联合检测对甲状腺功能减退症(甲减)的诊断效能.方法 目的选取2021年10月—2023年10月汶上县人民医院确诊的70例甲状腺功能障碍患者及同期于本院行健康体检的30例健康人员作为研究对象,分为亚甲减组(40例)、甲减组(30例)与健康组(30例).对比3组血清FT3、FT4、TSH水平,及血清FT3、FT4、TSH水平单项及联合检测对甲状腺功能的诊断效能.结果 3组血清FT3、FT4、TSH水平比较,差异有统计学意义(P均<0.05);3项指标联合检测对甲状腺功能的诊断效能最高(特异度98.01%,灵敏度91.22%,AUC=0.950).结论 血清FT3、FT4、TSH联合检测在甲减的临床诊断工作中具有较高的应用价值,可为后续的诊疗走向提供一定的临床依据.
Discussion on the Efficacy of Serum FT3,FT4,TSH Single and Combined Detection in Clinical Diagnosis of Hypothyroidism
Objective To explore the diagnostic efficacy of serum Free Triiodothyronine(FT3),Free Triiodothyronine(FT4)and Thyroid Stimulating Hormone(TSH)single and combined detection for hypothyrodism.Methods A total of 70 patients with thyroid dysfunction diagnosed in Wenshang County People's Hospital from October 2021 to October 2023 and 30 healthy personnel who underwent physical examination in our hospital during the same period were ob-jectively selected as the study objects,and were divided into sub-hypothyroidism group(40 cases),hypothyroidism group(30 cases)and healthy group(30 cases).Serum FT3,FT4 and TSH levels in 3 groups were compared,and the di-agnostic efficacy of single and combined detection of serum FT3,FT4 and TSH levels in thyroid function was com-pared.Results There were statistically significant differences in serum FT3,FT4 and TSH levels among 3 groups(all P<0.05).The combined detection of the three indexes had the highest diagnostic efficacy for thyroid function(specific-ity 98.01%,sensitivity 91.22%,AUC=0.950).Conclusion The combined detection of serum FT3,FT4 and TSH has high application value in the clinical diagnosis of thyroid function,and can provide a certain clinical basis for the sub-sequent diagnosis and treatment.

Thyroid functionJoint testingDiagnostic efficacy

李朋、程珊、李佳琪

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汶上县人民医院医学检验科,山东 济宁 272500

甲状腺功能 联合检测 诊断效能

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(13)