首页|注射用白眉蛇毒凝血酶联合奥美拉唑治疗急性消化道出血的临床效果分析

注射用白眉蛇毒凝血酶联合奥美拉唑治疗急性消化道出血的临床效果分析

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目的 分析对急性消化道出血患者实施注射用白眉蛇毒凝血酶联合奥美拉唑治疗的临床效果.方法 回顾性选取2022年1月—2024年1月乌兰察布市中心医院收治的150例急性消化道出血患者的临床资料,根据不同治疗方法分为研究组和对照组,各75例.研究组实施注射用白眉蛇毒凝血酶联合奥美拉唑治疗,对照组使用奥美拉唑钠治疗,比较两组临床疗效、临床指标水平、凝血功能指标、炎症因子指标以及不良反应发生率.结果 研究组治疗总有效率(93.33%)高于对照组(76.00%),差异有统计学意义(χ2=8.679,P<0.05).研究组的临床指标水平、凝血功能指标、炎症因子指标、不良反应发生率均优于对照组,差异有统计学意义(P均<0.05).结论 对急性消化道出血患者实施注射用白眉蛇毒血凝酶联合奥美拉唑进行治疗时可以有效缩短患者止血的时间,并且快速降低患者体内的炎症反应,使患者的临床治疗效果更佳,减少不良反应发生率.
Clinical Effect Analysis of Snake Venom Thrombin Combined with Omeprazole for Injection in The Treatment of Acute Gastrointestinal Bleeding
Objective To analyze the clinical effect of the treatment of acute gastrointestinal bleeding by injection of snake venom thrombin combined with omeprazole.Methods Clinical data of 150 patients with acute gastrointestinal hemorrhage admitted to Ulanqab Central Hospital from January 2022 to January 2024 were retrospectively selected and divided into study group and control group according to different treatment methods,with 75 cases in each group.The study group was treated with cobblehead venom thrombin combined with omeprazole for injection,while the con-trol group was treated with omeprazole sodium.The clinical efficacy,clinical indexes,coagulation function indexes,in-flammatory factor indexes and incidence of adverse reactions were compared between the two groups.Results The to-tal effective rate of the study group(93.33%)was higher than that of the control group(76.00%),the difference was statistically significant(χ2=8.679,P<0.05).The clinical indexes,coagulation function indexes and inflammatory fac-tors indexes incidence of adverse reactions of the study group were better than those of the control group,and the dif-ferences were statistically significant(all P<0.05).Conclusion In the treatment of patients with acute gastrointestinal bleeding,the combination of hemagglutinin and omeprazole for injection can effectively shorten the time of hemostasis and rapidly reduce the inflammatory response in the patient,so that the clinical treatment effect of the patient is better and the incidence of adverse reactions is reduced.

White eyebrow snake venom thrombinOmeprazoleAcute gastrointestinal bleeding

高伟华、赵杰、李晓敏

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乌兰察布市中心医院消化内科,内蒙古 乌兰察布 012000

白眉蛇毒凝血酶 奥美拉唑 急性消化道出血

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(13)