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分析溶栓治疗老年急性心肌梗死患者的临床疗效

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目的 探讨针对老年急性心肌梗死(Acute Myocardial Infarction,AMI)患者应用溶栓治疗的效果.方法 目的选取2022年5月—2023年5月呼伦贝尔市人民医院收治的66例老年AMI患者为研究对象,按治疗方法不同分为对照组(n=32)和观察组(n=34).对照组采用保守治疗,观察组采用尿激酶原静脉溶栓治疗.对比两组2 h胸痛症状缓解率、冠状动脉再通率及心血管不良事件发生率.结果 观察组2 h胸痛症状缓解率(85.29%)、冠状动脉再通率(82.35%)高于对照组,差异有统计学意义(χ2=5.583、5.318,P均<0.05).治疗后,观察组左心室收缩末期内径、舒张末内径、射血分数优于对照组,差异有统计学意义(P均<0.05).观察组不良心血管事件发生率(2.94%)低于对照组(21.88%),差异有统计学意义(χ2=3.913,P<0.05).结论 临床早期应用尿激酶原溶栓治疗老年AMI的效果显著.
Analyzing the Clinical Efficacy of Thrombolytic Therapy in Elderly Pa-tients with Acute Myocardial Infarction
Objective To explore the effectiveness of thrombolytic therapy for elderly patients with acute myocardial infarction(AMI).Methods A total of 66 elderly AMI patients admitted to the People's Hospital of Hulunbuir City from May 2022 to May 2023 were objectively selected as the study objects.They were divided into a control group(n=32)and an observation group(n=34)by difference treatment.The control group received conservative treatment,while the observation group received intravenous thrombolysis with prourokinase.The 2 h relief rate of chest pain symptoms,coronary artery recanalization rate,and incidence of vascular adverse events were compared between the two groups.Results The 2 h relief rate of chest pain symptoms(85.29%)and coronary artery recanalization rate(82.35%)in the observation group were higher than those in the control group,and the differences were statistically significant(χ2=5.583,5.318,both P<0.05).After treatment,the observation group had better left ventricular end systolic diameter,end diastolic diameter,and ejection fraction than the control group,the differences were statistically significant(all P<0.05).The incidence of adverse cardiovascular events in the observation group(2.94%)was lower than that in the con-trol group(21.88%),and the difference was statistically significant(χ2=3.913,P<0.05).Conclusion The early clinical application of prourokinase thrombolysis has a significant effect on the treatment of elderly AMI.

Acute myocardial infarction in the elderlyThrombolytic therapyClinical efficacyinfluence factor

郭丽云、王威、吴刚

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呼伦贝尔市人民医院心内科,内蒙古 呼伦贝尔 021000

呼伦贝尔市人民医院肿瘤外科,内蒙古 呼伦贝尔 021000

老年急性心肌梗死 溶栓治疗 临床疗效 影响因素

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(13)