首页|莫西沙星、糖皮质激素联合治疗慢性阻塞性肺疾病急性加重的疗效分析

莫西沙星、糖皮质激素联合治疗慢性阻塞性肺疾病急性加重的疗效分析

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目的 研究莫西沙星+糖皮质激素联用治疗慢性阻塞性肺疾病急性加重(Acute Exacerbation of Chronic Obstructive Pulmonary Disease,AECOPD)的效果与价值.方法 回顾性选取2022年12月—2023年12月聊城市东昌府区中医院收治的46例AECOPD患者的临床资料,按疗法的不同分为研究组和对照组,每组23例.对照组使用沙美特罗替卡松粉吸入剂治疗,研究组基于对照组使用莫西沙星治疗.比较两组疗效、肺功能、炎性因子.结果 研究组总有效率为100.00%,高于对照组的73.91%,差异有统计学意义(χ2=4.792,P<0.05).研究组肺功能指标、炎性因子水平优于对照组,差异有统计学意义(P均<0.05).结论 莫西沙星+糖皮质激素联用治疗AECOPD效果明显,改善患者肺功能指标、炎症水平,提升疗效.
Efficacy Analysis of Combination of Moxifloxacin and Glucocorticoids in Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Dis-ease
Objective To study the effect and value of moxifloxacin combined with glucocorticoid in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods The clinical data of 46 AECOPD patients admitted to Dongchangfu District Hospital of Traditional Chinese Medicine in Liaocheng City from December 2022 to December 2023 were retrospectively selected and divided into a study group and a control group based on the difference in therapies,with 23 cases in each group.The control group was treated with salmeterol ticarcoson powder inhaler,and the study group was treated with moxifloxacin based on the control group.Efficacy,lung function,and in-flammatory factors were compared between the two groups.Results The total effective rate of the study group was 100.00%,which was higher than 73.91%of the control group,and the difference was statistically significant(χ2=4.792,P<0.05).The lung function indexes and inflammatory factor levels of the study group were better than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion Moxifloxacin+glucocorti-coid combination is effective in the treatment of AECOPD,improving patients'lung function indexes,inflammation level,and enhancing the efficacy.

MoxifloxacinSulidieAcute exacerbation of chronic obstructive pulmonary diseasePulmonary function

薛冰、刘仲喆、王亚宁

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聊城市东昌府区中医院内科,山东 聊城 252000

聊城市江北水城旅游度假区于集镇中心卫生院,山东 聊城 252025

莫西沙星 沙美特罗替卡松粉吸入剂 慢性阻塞性肺疾病急性加重 肺功能

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(13)